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All cardiology trends
RisingCardiology · updated 18 Oct 2026

GLP-1 agonists in heart failure

Studies of GLP-1 receptor agonists such as semaglutide in patients with heart failure.

69PubDaily Trend Score
+40%new papers vs last year
26new trials registered
7new guidelines this year

Papers per year

Each bar is 12 months; the last one ends 17 Oct 2026. New trials in the same years: 14, 11, 14, 24, 26.

New guidelines and consensus this year

  1. ASN Kidney Health Guidance on the Cardiovascular-Kidney-Metabolic Syndrome
    J Am Soc Nephrol2026 Oct 1
  2. Kidney disease and heart failure: recent advances and current challenges: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference
    Kidney Int2026 Jun
  3. Ibero-American position statement on therapeutic recommendations for the preventive management of cardiovascular complications in latin-American patients with type 2 diabetes mellitus: consensus of the prevention council of the inter-American society of cardiology (SIAC-PREVENT)
    Diabetol Metab Syndr2026 Apr 12
  4. Kidney Disease and Heart Failure: Recent Advances and Current Challenges: Conclusions From a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference
    JACC Heart Fail2026 Apr
  5. Joint TOS/OMA/OAC Expert Guidance Statement on the Pharmacological Management of United States Adults With Overweight or Obesity Using the GRADE Approach
    Obesity (Silver Spring)2026 Apr

All papers from the last 12 months

591 papers (18 Oct 2025 – 17 Oct 2026), newest first. Loading the full list…

Open this search in PubMed
  1. Cardiovascular outcomes with tirzepatide versus semaglutide in type 2 diabetes
    J Diabetes Metab Disord2026 DecPMID 42840232
  2. Real-world prescribing patterns of SGLT2 inhibitors and GLP-1 receptor agonists in Type 2 diabetes with various ASCVD subtypes from a large tertiary referral center
    Am J Prev Cardiol2026 DecPMID 42827863
  3. Obesity and Cardiovascular Disease: An Obesity Medicine Association (OMA) Clinical Practice Statement (CPS) 2026
    Obes Pillars2026 DecPMID 42729919Review
  4. Association of tirzepatide with reverse cardiac remodeling and improved diastolic function in obesity-related HFpEF: A prospective real-world cohort study
    Int J Cardiol2026 Dec 1PMID 42710812
  5. Integrating the liver into the cardiovascular-kidney-metabolic syndrome: pathophysiology and therapeutic implications
    Curr Opin Nephrol Hypertens2026 Nov 1PMID 42683763Review
  6. From adiposity to multisystem morbidity: the case for weight loss as disease modification
    Lancet Diabetes Endocrinol2026 NovPMID 42660161Review
  7. Cardiorenal Mortality and Safety Outcomes of GLP-1 Receptor Agonists in Type 2 Diabetes With BMI Below 27 kg/m(2): A Target Trial Emulation
    Diabetes Obes Metab2026 NovPMID 42642357
  8. From pathobiology to prescribing in obesity-driven HFpEF: A systematic review and practical therapeutic framework
    Curr Probl Cardiol2026 NovPMID 42586458Systematic review
  9. Association of GLP-1 Receptor Agonist Use With Cardiovascular Outcomes and Mortality in Japanese Patients With Type 2 Diabetes: A Real-World Claims Database Study
    Diabetes Obes Metab2026 NovPMID 42581431
  10. Advances in Cardiovascular Pharmacotherapy. IX. Protection Against Major Adverse Cardiovascular Events by Glucagon-like Peptide-1 Receptor Agonists in Type 2 Diabetes Mellitus and Obesity
    J Cardiothorac Vasc Anesth2026 NovPMID 42580924Review

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How these numbers are counted

PubMed query, searched in titles and abstracts by publication date:

("glucagon-like peptide-1"[tiab] OR GLP-1[tiab] OR semaglutide[tiab] OR liraglutide[tiab]) AND "heart failure"[tiab]

Trials: ClinicalTrials.gov studies first submitted in each 12-month window that match the same terms. A query can miss synonyms or catch unrelated papers, so treat counts as approximate.