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All rheumatology trends
SteadyRheumatology · updated 18 Oct 2026

Gout

Gout management, including treat-to-target urate lowering.

32PubDaily Trend Score
-6%new papers vs last year
45new trials registered
2new guidelines this year

Papers per year

Each bar is 12 months; the last one ends 17 Oct 2026. New trials in the same years: 31, 31, 36, 41, 45.

New guidelines and consensus this year

  1. Gout, Hyperuricemia and Crystal-Associated Disease Network (G-CAN) consensus statement regarding labels and definitions for disease elements in calcium pyrophosphate crystal deposition (CPPD)
    Ann Rheum Dis2026 Jun 9
  2. Tophus severity grading and surgical treatment: Chinese Medical Doctor Association Multidisciplinary Expert Consensus Statement and Recommendations, 2025
    Int J Surg2026 Jan 1

All papers from the last 12 months

1,210 papers (18 Oct 2025 – 17 Oct 2026), newest first. Loading the full list…

Open this search in PubMed
  1. A decade iterative development of MOF-based uric acid luminescent sensors (2016-2026): From design strategy, mechanistic insights to portable detection
    Talanta2027 Jan 1PMID 42435544Review
  2. CA72-4 derived from synovial cells inhibits monosodium urate-induced macrophage M1 polarization by activating the TIGIT/SHP-1 axis through binding to Siglec-15
    Autoimmunity2026 Dec 31PMID 41920724
  3. Meta-analysis of handgrip strength in subjects with high-normal or mildly increased uric acid compared to low-normal levels reported as quartiles
    Gynecol Endocrinol2026 Dec 31PMID 41486688Meta-analysisSystematic review
  4. Multisystem effects of sodium-glucose cotransporter-2 inhibitors beyond glycaemic control: an umbrella review of systematic reviews and meta-analyses
    J Diabetes Metab Disord2026 DecPMID 42856812Review
  5. Gut microbiota-mediated uric acid metabolism: Novel insights for developing urate-lowering and anti-gout medications
    Pharm Sci Adv2026 DecPMID 42751478Review
  6. Integrated transcriptomics and metabolomics reveal suppression of the PPAR α/γ pathway linking purine metabolism disorder to high-protein diet-induced hyperuricemia in goslings
    Anim Nutr2026 DecPMID 42741484
  7. Single-atom nanozyme-based wireless microfluidic sensing platform for noninvasive hyperuricemia diagnosis
    Biosens Bioelectron2026 Dec 1PMID 42571737
  8. Male reproductive surgeries and long-term kidney outcomes: a Mendelian randomization and meta-analysis of UK Biobank and FinnGen
    Ren Fail2026 DecPMID 42549566Meta-analysis
  9. Regarding 'incidence and prevalence of gout in Eastern China from 2011 to 2021: a retrospective population-based study'
    Ann Med2026 DecPMID 41574931
  10. Repurposing the anti-gout drug benzbromarone for the treatment of glioma
    Cell Cycle2026 DecPMID 41201217

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How these numbers are counted

PubMed query, searched in titles and abstracts by publication date:

gout[tiab]

Trials: ClinicalTrials.gov studies first submitted in each 12-month window that match the same terms. A query can miss synonyms or catch unrelated papers, so treat counts as approximate.