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All cardiology trends
SteadyCardiology · updated 18 Oct 2026

HFpEF

Heart failure with preserved ejection fraction.

54PubDaily Trend Score
+24%new papers vs last year
100new trials registered
10new guidelines this year

Papers per year

Each bar is 12 months; the last one ends 17 Oct 2026. New trials in the same years: 77, 86, 91, 108, 100.

New guidelines and consensus this year

  1. Pharmacological treatment strategies to prevent heart failure across the cardiovascular-kidney-metabolic spectrum: an EJHF Expert Consensus Statement
    Eur J Heart Fail2026 Oct 1
  2. 2026 focsused update incorporated into the Japanese society of echocardiography 2023 practice guidance for the implementation of stress echocardiography "stress echocardiography using the Valsalva maneuver"
    J Echocardiogr2026 Sep
  3. Kidney disease and heart failure: recent advances and current challenges: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference
    Kidney Int2026 Jun
  4. Exercise & Sports Science Australia Position Statement on exercise training in patients with chronic heart failure: 2025 update
    J Sci Med Sport2026 May
  5. Kidney Disease and Heart Failure: Recent Advances and Current Challenges: Conclusions From a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference
    JACC Heart Fail2026 Apr

All papers from the last 12 months

2,518 papers (18 Oct 2025 – 17 Oct 2026), newest first. Loading the full list…

Open this search in PubMed
  1. Presumed right atrial myxoma causing mechanical inflow obstruction and a heart-failure-with-preserved-ejection-fraction-mimicking phenotype in a resource-limited setting: A case report
    Radiol Case Rep2026 DecPMID 42871978
  2. Clinical outcomes of sacubitril/valsartan in patients with mildly reduced or preserved ejection fraction and acute heart failure: a multi-institutional study
    Ann Med2026 DecPMID 42860551
  3. Persistent C-reactive protein elevation and incident heart failure in adults at increased cardiovascular risk: A multinational electronic health record study
    Int J Cardiol2026 Dec 1PMID 42749086
  4. Obesity and Cardiovascular Disease: An Obesity Medicine Association (OMA) Clinical Practice Statement (CPS) 2026
    Obes Pillars2026 DecPMID 42729919Review
  5. Association of tirzepatide with reverse cardiac remodeling and improved diastolic function in obesity-related HFpEF: A prospective real-world cohort study
    Int J Cardiol2026 Dec 1PMID 42710812
  6. Prediction is not diagnosis: Translating explainable machine learning into OSA screening in HFpEF
    Int J Cardiol2026 Dec 1PMID 42586438
  7. Combined podocyte, fibrotic and echocardiographic correlates of an operationally defined subclinical cardiorenal phenotype in chronic kidney disease: an exploratory study
    Ren Fail2026 DecPMID 42443716
  8. Predicting major adverse cardiovascular and cerebrovascular events in chronic heart failure: a machine learning study
    Ann Med2026 DecPMID 42286995
  9. Prognostic value of peak tricuspid regurgitation velocity in hospitalized patients with heart failure with preserved ejection fraction: an multi-institutional study
    Ann Med2026 DecPMID 41961002
  10. The diagnostic yield of a structured comorbidity workup in a real-life outpatient population with obstructive sleep apnea: a cross-sectional study
    Ann Med2026 DecPMID 41640204

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How these numbers are counted

PubMed query, searched in titles and abstracts by publication date:

HFpEF[tiab] OR "preserved ejection fraction"[tiab]

Trials: ClinicalTrials.gov studies first submitted in each 12-month window that match the same terms. A query can miss synonyms or catch unrelated papers, so treat counts as approximate.