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All hematology trends
RisingHematology · updated 18 Oct 2026

Measurable residual disease

Detecting residual disease after treatment of blood cancers.

78PubDaily Trend Score
+41%new papers vs last year
297new trials registered
7new guidelines this year

Papers per year

Each bar is 12 months; the last one ends 17 Oct 2026. New trials in the same years: 198, 195, 248, 248, 297.

New guidelines and consensus this year

  1. B-Cell Lymphomas, Version 4.2026, NCCN Clinical Practice Guidelines In Oncology
    J Natl Compr Canc Netw2026 Sep
  2. Consensus Statement on ctDNA Minimal Residual Disease Testing in Early Stage NSCLC: A Delphi Study by the Asian Thoracic Oncology Research Group
    J Thorac Oncol2026 Aug
  3. NCCN Guidelines® Insights: Acute Myeloid Leukemia, Version 3.2026
    J Natl Compr Canc Netw2026 Jun
  4. [Recommendations from the GBMHM and the Fi-LMC for the diagnosis and management of chronic myeloid leukemia]
    Bull Cancer2026 Apr
  5. 2025 update on MRD in acute myeloid leukemia: a consensus document from the ELN-DAVID MRD Working Party
    Blood2026 Mar 12

All papers from the last 12 months

1,709 papers (18 Oct 2025 – 17 Oct 2026), newest first. Loading the full list…

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  1. Microhaplotype-based chimerism analysis for sensitive monitoring following allogeneic hematopoietic stem cell transplantation
    Clin Chim Acta2027 Feb 15PMID 42648527
  2. MicroRNA profiles as diagnostic tools in pediatric acute lymphoblastic leukemia
    Clin Chim Acta2027 Feb 15PMID 42641935Review
  3. Digital droplet PCR and liquid biopsy in acute myeloid Leukemia: bridging translational research and clinical practice
    Clin Chim Acta2027 Feb 15PMID 42624191Review
  4. Thermal-enhanced atypical suboptimal PAM-dependent CRISPR/Cas12a amplification for detecting BCR1-Type PML::RARα fusion and L217F mutation
    Biosens Bioelectron2027 Jan 1PMID 42731312
  5. CRISPR-Cas12a-based liquid biopsy technology: challenges in large-scale clinical application
    Clin Chim Acta2027 Jan 1PMID 42379464Review
  6. TIM-3 as an immune and leukemia stem-cell biomarker in acute myeloid leukemia: diagnostic laboratory and translational perspectives
    Clin Chim Acta2027 Jan 1PMID 42309212Review
  7. Frontline therapies for adult patients with newly diagnosed Philadelphia chromosome-negative B-cell acute lymphoblastic leukemia: a systematic literature review
    Hematology2026 Dec 31PMID 42711755Systematic review
  8. Serologic follow-up in patients with multiple myeloma without repeated bone marrow studies: a single-institution experience
    Hematology2026 Dec 31PMID 42685232
  9. Identification of coilin in bone marrow as a potential neuroblastoma tumor progression marker transcriptionally regulated by MYCN
    Cancer Biol Ther2026 Dec 31PMID 41423806
  10. A streamlined hybrid-capture and genome-wide multi-omic platform for highly sensitive ctDNA minimal residual disease monitoring
    J Liq Biopsy2026 DecPMID 42830887

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Bispecific antibodies in myeloma

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+46%new papersScore 78
20212026

Teclistamab, elranatamab and talquetamab in multiple myeloma.

461 papers / yr49 new trials4 new guidelines
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Gene therapy for sickle cell and thalassaemia

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+27%new papersScore 72
20212026

CRISPR-based and lentiviral gene therapies for haemoglobin disorders.

238 papers / yr8 new trials2 new guidelines
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CAR-T in blood cancers

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+18%new papersScore 70
20212026

Chimeric antigen receptor T-cell therapy in lymphoma, myeloma and leukaemia.

Key point: CAR T-cell therapy has emerged as an effective option for refractory or progressive mantle cell lymphoma after prior covalent BTK inhibitor treatment.

1,955 papers / yr233 new trials11 new guidelines
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Immune thrombocytopenia

Rising
+25%new papersScore 63
20212026

ITP and its newer treatments.

Key point: Adult ITP care incorporates newer thrombopoietin receptor agonists and small molecule kinase inhibitors, emphasizing thrombotic risk and quality of life.

683 papers / yr92 new trials3 new guidelines
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DOACs in cancer-associated thrombosis

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+29%new papersScore 62
20212026

Direct oral anticoagulants for venous thromboembolism in people with cancer.

183 papers / yr7 new trials2 new guidelines
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Myelofibrosis treatment

Rising
-6%new papersScore 55
20212026

JAK inhibitors and newer drugs in myelofibrosis.

Key point: Ruxolitinib-based combination regimens showed improved spleen and symptom responses with acceptable safety, with efficacy significantly influenced by prior JAK inhibitor exposure.

147 papers / yr18 new trials1 new guideline
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How these numbers are counted

PubMed query, searched in titles and abstracts by publication date:

"measurable residual disease"[tiab] OR "minimal residual disease"[tiab]

Trials: ClinicalTrials.gov studies first submitted in each 12-month window that match the same terms. A query can miss synonyms or catch unrelated papers, so treat counts as approximate.