Radioligand therapy
Radioactive drugs that target tumour receptors, such as lutetium-177 PSMA.
Key point
Most international guidelines endorse 177Lu-PSMA-617 for PSMA-positive metastatic castration-resistant prostate cancer after prior ARPI and taxane chemotherapy.
From: Guideline of guidelines: lutetium-177 PSMA radioligand therapy in advanced prostate cancer (BJU Int, 2026 Sep) ↗Papers per year
Each bar is 12 months; the last one ends 17 Oct 2026. New trials in the same years: 66, 85, 99, 98, 95.
New guidelines and consensus this year
All papers from the last 12 months
1,445 papers (18 Oct 2025 – 17 Oct 2026), newest first. Loading the full list…
- [(177)Lu] Lu-PSMA-I&T for prostate cancer radioligand therapy: A radiopharmacy's journey from synthesis to cost-effectivenessAppl Radiat Isot2026 DecPMID 42696922
- Development of covalent agonists for the muscarinic acetylcholine receptorBioorg Med Chem2026 DecPMID 42673835
- Clinical and economic outcomes of cabazitaxel versus Lu-PSMA in mCRPC: a US perspectiveJ Med Econ2026 DecPMID 42565339
- First-in-human evaluation of [(18)F]-AlF-NOTA-neurotensin for NTSR1-targeted imaging of prostate cancer: a head-to-head comparison with [(68)Ga]Ga-PSMA-617Ann Med2026 DecPMID 42304982
- Repurposing radiopharmaceutical carriers for targeted drug delivery and theranostics: A translational frameworkPharm Sci Adv2026 DecPMID 42027782Review
- Click chemistry-driven modular radionuclide labeling of HER2 nanobody: An integrated platform for diagnosis and treatment of precision oncologyEur J Med Chem2026 Nov 5PMID 42419170
- Unusual paraneoplastic thrombocytosis in small bowel neuroendocrine tumor responding to (177)Lu-DOTATATEJCEM Case Rep2026 NovPMID 42871284
- Near-complete Response of Bilateral Adrenal Metastases to 177Lu-PSMA Therapy in Castration-resistant Prostate Cancer on Posttherapeutic SPECT-CT Follow UpClin Nucl Med2026 Nov 1PMID 42853992
- Publication trends and knowledge structure of prostate-specific membrane antigen radioligand therapy for prostate cancer: a bibliometric analysis, 2015-2025Nucl Med Commun2026 Nov 1PMID 42844992
- A case of metastasectomy following multiple courses of radionuclide therapy for distant metastatic pheochromocytomaJCEM Case Rep2026 NovPMID 42831206
More oncology trends
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Deep learning on digital pathology slides.
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Palbociclib, ribociclib and abemaciclib in hormone receptor-positive breast cancer.
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Drugs targeting KRAS mutations, such as sotorasib and adagrasib.
Multi-cancer early detection
Blood tests that screen for many cancers at once.
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How these numbers are counted
PubMed query, searched in titles and abstracts by publication date:
radioligand[tiab] OR lutetium[tiab] OR 177Lu[tiab] OR "PSMA-617"[tiab]Trials: ClinicalTrials.gov studies first submitted in each 12-month window that match the same terms. A query can miss synonyms or catch unrelated papers, so treat counts as approximate.