Tirzepatide in cardiovascular disease
Research on tirzepatide, a dual GIP/GLP-1 receptor agonist, and heart and vascular outcomes.
Papers per year
Each bar is 12 months; the last one ends 17 Oct 2026. New trials in the same years: 1, 4, 9, 29, 42.
New guidelines and consensus this year
- Incretin-based therapies in peri- and postmenopausal women with obesity: an expert position statement from the Spanish Menopause SocietyMaturitas2026 Oct
- Pharmacologic Treatments With Lifestyle Modifications in Nonpregnant Adults With Overweight or Obesity in Outpatient Settings: A Living Clinical Guideline From the American College of Physicians (April 2026)Ann Intern Med2026 Aug
- Swiss obesity clinical practice guidanceSwiss Med Wkly2026 May 19
- [Individualizing antihypertensive therapy in diabetes mellitus. Guidelines of the Austrian Diabetes Association (Update 2026)]Wien Klin Wochenschr2026 May
- Joint TOS/OMA/OAC Expert Guidance Statement on the Pharmacological Management of United States Adults With Overweight or Obesity Using the GRADE ApproachObesity (Silver Spring)2026 Apr
All papers from the last 12 months
395 papers (18 Oct 2025 – 17 Oct 2026), newest first. Loading the full list…
- Cardiovascular outcomes with tirzepatide versus semaglutide in type 2 diabetesJ Diabetes Metab Disord2026 DecPMID 42840232
- Incretin therapy prescription in a high cardiovascular risk population: Insights from a cardiology-based cardiometabolic programAm J Prev Cardiol2026 DecPMID 42828252
- Association of tirzepatide with reverse cardiac remodeling and improved diastolic function in obesity-related HFpEF: A prospective real-world cohort studyInt J Cardiol2026 Dec 1PMID 42710812
- Cost-effectiveness of tirzepatide versus semaglutide for patients with obesity or overweight in the US: evidence from the SURMOUNT-5 head-to-head phase-3 trialJ Med Econ2026 DecPMID 42012820
- Tirzepatide attenuates cardiac microvascular injury and ferroptosis-related lipid peroxidation in diabetic mice: endothelial responses in the context of partial PRKN silencingEur J Pharmacol2026 Nov 25PMID 42826814
- Current review of glucagon-like peptide 1 receptor agonists and risk of nonarteritic anterior ischemic optic neuropathyJ Endocr Soc2026 NovPMID 42857401Review
- Real-world effectiveness of 6-month tirzepatide therapy on body weight and composition in adults with overweight and obesityJ Diabetes Complications2026 NovPMID 42805130
- Integrating the liver into the cardiovascular-kidney-metabolic syndrome: pathophysiology and therapeutic implicationsCurr Opin Nephrol Hypertens2026 Nov 1PMID 42683763Review
- From adiposity to multisystem morbidity: the case for weight loss as disease modificationLancet Diabetes Endocrinol2026 NovPMID 42660161Review
- Cardiorenal Mortality and Safety Outcomes of GLP-1 Receptor Agonists in Type 2 Diabetes With BMI Below 27 kg/m(2): A Target Trial EmulationDiabetes Obes Metab2026 NovPMID 42642357
More cardiology trends
All specialties →Pulsed field ablation
An ablation energy for atrial fibrillation that uses electric fields instead of heat or cold.
Semaglutide and cardiovascular outcomes
Research on semaglutide and major cardiovascular events.
Finerenone
A non-steroidal mineralocorticoid receptor antagonist studied in kidney disease and heart failure.
Left atrial appendage occlusion
Closing the left atrial appendage with a device to reduce stroke risk in atrial fibrillation.
Coronary drug-coated balloons
Balloons coated with an antiproliferative drug, used in coronary arteries.
Photon-counting CT
A newer CT detector technology, studied for cardiac and coronary imaging.
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How these numbers are counted
PubMed query, searched in titles and abstracts by publication date:
tirzepatide[tiab] AND (cardiovascular[tiab] OR cardiac[tiab] OR heart[tiab])Trials: ClinicalTrials.gov studies first submitted in each 12-month window that match the same terms. A query can miss synonyms or catch unrelated papers, so treat counts as approximate.