Aesthetic botulinum toxin
Botulinum toxin for facial lines and aesthetic use.
Key point
In men, botulinum toxin type A for upper facial wrinkles had high response rates, with minor and transient adverse events.
From: Minimally Invasive Aesthetic Treatments in Men: A Systematic Review and Meta-Analysis (Dermatol Surg, 2026 Oct 1) ↗Papers per year
Each bar is 12 months; the last one ends 17 Oct 2026. New trials in the same years: 28, 17, 25, 14, 19.
All papers from the last 12 months
239 papers (18 Oct 2025 – 17 Oct 2026), newest first. Loading the full list…
- Antidepressant effects of facial botulinum toxin a injections: Insights from randomized controlled trialsJ Affect Disord2026 Dec 15PMID 42669382Meta-analysisSystematic review
- From uniformity to individuality: Computational modelling provides a mechanistic rationale for weight-adjusted botulinum neurotoxin a dosingToxicon2026 Nov 1PMID 42532319
- Optimizing Autologous Fat Grafting: A Systematic Review of Enhancement Strategies and Graft SurvivalAesthet Surg J2026 Oct 15PMID 41259287Systematic review
- Beyond reconstruction: minimally invasive aesthetic and regenerative medicine in postoperative oral and maxillofacial surgeryOral Maxillofac Surg2026 Oct 13PMID 42864448Review
- Treatment of hypertrophic scars using fractional CO2 laser alone in comparison with adding botulinium toxin either intalesional injection or assisted drug deliveryLasers Med Sci2026 Oct 2PMID 42825928RCT
- A Multimodal Approach to Extended Periorbital Rejuvenation: Clinical Outcomes and Time Course in a Prospective Single-Centre StudyClin Cosmet Investig Dermatol2026PMID 42836122
- Minimally Invasive Aesthetic Treatments in Men: A Systematic Review and Meta-AnalysisDermatol Surg2026 Oct 1PMID 42574235Meta-analysisSystematic review
- Marin-Amat syndrome: a comprehensive review of pathophysiology, clinical presentation, and managementOrbit2026 OctPMID 42504772Review
- Lip Rejuvenation Options in the Youthful PopulationFacial Plast Surg2026 OctPMID 42320880Review
- Efficacy and Safety of Microneedle Fractional Radiofrequency Combined with Botulinum Toxin Type A for Periorbital Aging: A Retrospective Cohort StudyClin Cosmet Investig Dermatol2026PMID 42827935
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How these numbers are counted
PubMed query, searched in titles and abstracts by publication date:
"botulinum toxin"[tiab] AND (aesthetic[tiab] OR cosmetic[tiab] OR wrinkle*[tiab] OR glabellar[tiab])Trials: ClinicalTrials.gov studies first submitted in each 12-month window that match the same terms. A query can miss synonyms or catch unrelated papers, so treat counts as approximate.