AI chatbots in mental health
Chatbots and language models used for mental health support.
Key point
PDC30, a self-guided automated intervention with an AI-powered counseling chatbot, improved caregiver depression, burden, and positive gains versus waitlist at 1 month.
From: Intervention Without Borders - an Automated Self-Guided AI-Enhanced Psychoeducation Intervention for Dementia Caregivers: Parallel-Group Randomized Waitlist-Controlled Trial (Am J Geriatr Psychiatry, 2026 Oct) ↗Papers per year
Each bar is 12 months; the last one ends 17 Oct 2026. New trials in the same years: 11, 12, 24, 28, 48.
All papers from the last 12 months
817 papers (18 Oct 2025 – 17 Oct 2026), newest first. Loading the full list…
- Artificial Intelligence in suicide prevention: promise, peril, and clinical implications for clinical practiceDialogues Clin Neurosci2027 DecPMID 42862709Review
- Language and cultural prompts influence large language models' responses to culturally anchored mental health attitudesPEC Innov2026 DecPMID 42831130
- The effects of artificial intelligence-based chatbots on mental health: A systematic review and three-level meta-analysisPsychiatry Res2026 DecPMID 42743601Meta-analysisSystematic review
- PKFAR: psychiatry knowledge-fused augmented reasoning with large language modelsHealth Inf Sci Syst2026 DecPMID 41982804
- Ensemble of transformers for depression emotion classificationCogn Neurodyn2026 DecPMID 41971719
- Enhancing explainability and performance of the depression detection model on social media utilizing feature engineering and LLMsHealth Inf Sci Syst2026 DecPMID 41883984
- Associations of artificial intelligence use at work with psychological distress, loneliness, and life satisfaction among employed US adultsPrev Med Rep2026 NovPMID 42830789
- AI-Mediated Mental Health Support: The Role of Attachment Orientation and Psychological DistressCyberpsychol Behav Soc Netw2026 NovPMID 42808327
- On-premises open-source large language models for privacy-preserving multimodal depression screeningInt J Med Inform2026 Nov 1PMID 42379124
- The engagement-validation loop: Sycophancy, anthropomorphic projection, and clinical risk in informal AI-based mental health supportJ Affect Disord2026 Nov 1PMID 42269974
More psychiatry trends
All specialties →GLP-1 drugs, addiction and mood
GLP-1 based medicines studied in alcohol and substance use, and their psychiatric effects.
Digital mental health apps
Smartphone apps and digital programmes for depression and anxiety.
Key point: Smartphone-delivered lifestyle medicine reduced depressive symptoms more than waitlist control and maintained within-group improvements through 3-month follow-up in probable depression.
ADHD in adults
Diagnosis and treatment of ADHD in adults.
Loneliness and health
Loneliness and social isolation as risk factors.
Gut microbiome and mental health
Links between the gut microbiome and depression or anxiety.
Psilocybin therapy
Psilocybin-assisted therapy for depression and other conditions.
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How these numbers are counted
PubMed query, searched in titles and abstracts by publication date:
(chatbot*[tiab] OR "large language model*"[tiab] OR ChatGPT[tiab]) AND ("mental health"[tiab] OR psychiatr*[tiab] OR depress*[tiab])Trials: ClinicalTrials.gov studies first submitted in each 12-month window that match the same terms. A query can miss synonyms or catch unrelated papers, so treat counts as approximate.