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All otorhinolaryngology trends
RisingOtorhinolaryngology · updated 18 Oct 2026

Biologics for nasal polyps

Dupilumab and other biologics for chronic rhinosinusitis with nasal polyps.

56PubDaily Trend Score
+28%new papers vs last year
18new trials registered
1new guidelines this year

Papers per year

Each bar is 12 months; the last one ends 17 Oct 2026. New trials in the same years: 15, 19, 23, 20, 18.

New guidelines and consensus this year

  1. Advances in the management of chronic rhinosinusitis with nasal polyps. Review of multidisciplinary strategies and innovations in biological treatments
    Acta Otorrinolaringol Esp (Engl Ed)2026 May-Jun

All papers from the last 12 months

522 papers (18 Oct 2025 – 17 Oct 2026), newest first. Loading the full list…

Open this search in PubMed
  1. Depemokimab: A twice yearly anti-IL 5 biologic for chronic rhinosinusitis with nasal polyps (CRSwNP) - A narrative review
    Hum Vaccin Immunother2026 DecPMID 42234701Review
  2. Beyond biomarkers: the role of clinical factors associated with biologic therapy response in severe asthma
    Ann Med2026 DecPMID 41672447
  3. Identification of severe eosinophilic asthma in patients with chronic rhinosinusitis and nasal polyps who are awaiting sinus surgery
    J Allergy Clin Immunol Glob2026 NovPMID 42733480
  4. Postoperative Recurrence of Chronic Rhinosinusitis with Nasal Polyps: Endotype Mechanisms, Predictive Models, and Novel Strategies for Precision Treatment
    Int Arch Allergy Immunol2026 Oct 15PMID 42879369Review
  5. Pocket guide Biologics in upper and lower airway diseases 2026 by EUFOREA
    Rhinology2026 Oct 15PMID 42878116
  6. A Bibliometric Analysis of Research Interest in Dupilumab for Chronic Rhinosinusitis With Nasal Polyposis
    Perm J2026 Oct 15PMID 42876213Review
  7. Second-line dupilumab after anti-IL5/Rα failure: remission rates and clinical outcomes in severe asthma
    J Allergy Clin Immunol Pract2026 Oct 14PMID 42874915
  8. Efficacy and safety of tezepelumab in Japanese patients with chronic rhinosinusitis with nasal polyps: A subpopulation analysis of the randomized WAYPOINT study
    Auris Nasus Larynx2026 Oct 13PMID 42868896
  9. Sustained clinical control after intranasal corticosteroid withdrawal in chronic rhinosinusitis with nasal polyps (CRSwNP) treated with dupilumab
    Eur Arch Otorhinolaryngol2026 Oct 13PMID 42867640
  10. Surgery and/or biologics in chronic rhinosinusitis with nasal polyps: EUFOREA/EPOS consensus paper
    Rhinology2026 Oct 10PMID 42858259

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How these numbers are counted

PubMed query, searched in titles and abstracts by publication date:

("chronic rhinosinusitis"[tiab] OR "nasal polyp*"[tiab]) AND (biologic*[tiab] OR dupilumab[tiab] OR mepolizumab[tiab] OR omalizumab[tiab] OR tezepelumab[tiab])

Trials: ClinicalTrials.gov studies first submitted in each 12-month window that match the same terms. A query can miss synonyms or catch unrelated papers, so treat counts as approximate.