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All endocrinology trends
SteadyEndocrinology · updated 18 Oct 2026

Cell therapy for type 1 diabetes

Islet transplantation and stem cell-derived beta cells.

24PubDaily Trend Score
-4%new papers vs last year
5new trials registered
0new guidelines this year

Papers per year

Each bar is 12 months; the last one ends 17 Oct 2026. New trials in the same years: 0, 2, 0, 1, 5.

All papers from the last 12 months

148 papers (18 Oct 2025 – 17 Oct 2026), newest first. Loading the full list…

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  1. Retrievable "sea-island" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival
    Bioact Mater2027 JanPMID 42598441
  2. IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells
    Islets2026 Dec 31PMID 42430551
  3. Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review
    Islets2026 Dec 31PMID 42017902Review
  4. MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats
    Organogenesis2026 Dec 31PMID 41774510
  5. Stage-Adapted Disease-Modifying Therapy in Type 1 Diabetes
    Diabetes Obes Metab2026 NovPMID 42587353Review
  6. Organotypic vascularization improves maturation of human stem cell-derived islets and restores normoglycemia in diabetic mice
    Cell Stem Cell2026 Oct 16PMID 42887499
  7. Protective IFIH1 variant reduces islet stress and dysfunction in a type 1 diabetes genetic background
    iScience2026 Oct 16PMID 42787837
  8. MenSC-EV-derived HSPA5 activates the AKT/mTOR axis to suppress ferroptosis in type 1 diabetes mellitus-associated ovarian dysfunction
    Free Radic Biol Med2026 Oct 13PMID 42869305
  9. Immune Biomarkers of Islet Transplant Rejection Revealed by Synthetic Immunological Niche
    Adv Sci (Weinh)2026 Oct 8PMID 42850666
  10. Oxidative Stress, Post-Translational Modifications, and Type 1 Diabetes Pathogenesis
    Immunol Rev2026 OctPMID 42876362Review

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How these numbers are counted

PubMed query, searched in titles and abstracts by publication date:

"type 1 diabetes"[tiab] AND ("stem cell-derived"[tiab] OR "islet transplant*"[tiab] OR "beta cell replacement"[tiab] OR zimislecel[tiab])

Trials: ClinicalTrials.gov studies first submitted in each 12-month window that match the same terms. A query can miss synonyms or catch unrelated papers, so treat counts as approximate.