CGRP-targeted migraine treatment
Gepants and anti-CGRP antibodies for migraine.
Papers per year
Each bar is 12 months; the last one ends 17 Oct 2026. New trials in the same years: 33, 36, 34, 31, 32.
New guidelines and consensus this year
- Anti-CGRP Monoclonal Antibodies in Chronic Migraine: A Position Statement of the Brazilian Academy of Headache and Orofacial PainCureus2026 Aug
- Sex-specific management of migraine a systematic review and consensus statement from the European Headache Federation (EHF)J Headache Pain2026 Apr 17
- [Acute migraine treatment : recommendations to optimize management]Rev Med Liege2026 Apr
- The state of insurance coverage of calcitonin gene-related peptide-targeted medications and its impact on the implementation of the American Headache Society's 2024 consensus statement: An interrupted time-series analysisHeadache2026 Apr
- [Joint practical guideline of the Hungarian Pain Society Chronic Headache Working Group and the Hungarian Headache Society on the use of calcitonin gene-related peptide (CGRP)-targeting therapies in migraine]Orv Hetil2025 Dec 14
All papers from the last 12 months
612 papers (18 Oct 2025 – 17 Oct 2026), newest first. Loading the full list…
- Paeoniae Radix Alba-Chuanxiong Rhizoma herbal pair alleviates trigeminal nucleus caudalis neuroinflammation in chronic migraine associated with P2Y12R/PPARγ-related NF-κB signalingJ Ethnopharmacol2027 Jan 10PMID 42431281
- Xiongzhi Qufeng Zhitong Granule alleviates nitroglycerin-induced migraine-like nociception and central neuroinflammation by regulating the HMGB1 / TRPV1 / MAPK signaling axisJ Ethnopharmacol2027 Jan 10PMID 42398658
- Targeting the microbiome in pediatric migraine: gastrointestinal manifestations and the therapeutic role of Bifidobacterium longumGut Microbes2026 Dec 31PMID 41454664
- Mechanisms of neuroimmune crosstalk in vestibular disorders: Linking inflammation with neural circuit dysfunction (Review)Int J Mol Med2026 DecPMID 42852636Review
- Real-world treatment switching and healthcare costs of onabotulinumtoxinA and calcitonin gene-related peptide monoclonal antibodies in Medicare patients with chronic migraine: a retrospective claims analysisJ Med Econ2026 DecPMID 41725292
- Response to "Route of IL-4 administration in Li et al.: an inconsistency between the methods and Section 4.4"Brain Behav Immun2026 NovPMID 42764134
- Physiologically Based Pharmacokinetic Modeling to Assess Transporter-Mediated Drug-Drug Interactions in Support of Labeling Recommendations for Zavegepant Nasal SprayClin Pharmacol Ther2026 NovPMID 42698006
- Targeting peroxynitrite production in a model of persistent temporomandibular disorder comorbid with migraineBr J Pharmacol2026 NovPMID 42527979
- Late-pregnancy oxytocin alleviates neuroinflammation and hyperalgesia in chronic migraine model via PVN to NTS oxytocinergic projections and ECM-receptor interaction signalingBrain Behav Immun2026 NovPMID 42472609
- The glymphatic system as a mechanistic bridge between migraine and sleep: Evidence from clinical studies and animal modelsNeurobiol Dis2026 Oct 16PMID 42887656Review
More neurology trends
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Plasma p-tau and other blood biomarkers for Alzheimer's pathology.
Focused ultrasound for tremor
MR-guided focused ultrasound for essential tremor and Parkinson's disease.
Key point: MRgFUS thalamotomy is safe, effective, and durable for refractory essential tremor; it appears safe and effective for Parkinson disease tremor, with uncertain durability.
Auricular vagus nerve stimulation
Studies of transcutaneous auricular vagus nerve stimulation (taVNS), a non-invasive neuromodulation technique.
Tenecteplase in stroke
Tenecteplase as the thrombolytic for acute ischaemic stroke.
Key point: Intravenous tenecteplase before thrombectomy showed benefit in ASPECTS <8, but no functional improvement and possible safety concerns in ASPECTS 8-10.
Post-stroke dysphagia
Studies of swallowing disorders after stroke and their treatment, including neuromodulation.
Anti-amyloid antibodies
Lecanemab, donanemab and related antibodies for early Alzheimer's disease.
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How these numbers are counted
PubMed query, searched in titles and abstracts by publication date:
(CGRP[tiab] OR "calcitonin gene-related peptide"[tiab] OR gepant*[tiab] OR erenumab[tiab] OR fremanezumab[tiab] OR galcanezumab[tiab] OR rimegepant[tiab] OR atogepant[tiab]) AND migraine[tiab]Trials: ClinicalTrials.gov studies first submitted in each 12-month window that match the same terms. A query can miss synonyms or catch unrelated papers, so treat counts as approximate.