Tenecteplase in stroke
Tenecteplase as the thrombolytic for acute ischaemic stroke.
Key point
Intravenous tenecteplase before thrombectomy showed benefit in ASPECTS <8, but no functional improvement and possible safety concerns in ASPECTS 8-10.
From: Effect of Baseline ASPECTS on Tenecteplase Efficacy Before Thrombectomy in Acute Large-Vessel Occlusion Stroke: A Post Hoc Analysis of the BRIDGE-TNK Randomized Trial (Neurology, 2026 Sep 22) ↗Papers per year
Each bar is 12 months; the last one ends 17 Oct 2026. New trials in the same years: 11, 21, 12, 25, 32.
All papers from the last 12 months
255 papers (18 Oct 2025 – 17 Oct 2026), newest first. Loading the full list…
- Neutrophil to Lymphocyte Ratio and Neurological Outcome in Ischemic Stroke at 4.5 to 24 Hours: A Post Hoc Analysis of TRACE-III TrialNeurol Ther2026 Oct 16PMID 42886317
- Tenecteplase, alteplase, and endovascular thrombectomy in extended-window acute ischemic stroke with intracranial large-vessel occlusion: a Bayesian network meta-analysisJ Neurol2026 Oct 16PMID 42886241Review
- Intra-arterial thrombolytics after endovascular thrombectomy for acute ischemic stroke: A network meta-analysis of RCTsJ Neurol Sci2026 Oct 15PMID 42480380Systematic review
- Balancing Ischemia and Hemorrhage After Tenecteplase in Wake-Up StrokeJACC Case Rep2026 Oct 14PMID 42559778
- Thrombolysis in the Delayed Treatment Window for Acute Ischemic Stroke: Updated Systematic Review and Meta-AnalysisStroke2026 Oct 13PMID 42866880
- Stroke thrombectomy of a mural thrombus in a severe dolichoectatic basilar artery with double parallel large stent retrievers and Sofia 88J Neurointerv Surg2026 Oct 13PMID 40473383
- Clinical outcomes after intravenous thrombolysis for acute ischemic stroke in low- and middle-income countries: a pooled analysis of 67,917 patients and systematic reviewNeurol Res2026 Oct 11PMID 42860667Review
- Effectiveness and safety of tenecteplase for acute ischaemic stroke at primary stroke centres: a multicentre retrospective studyStroke Vasc Neurol2026 Oct 7PMID 42849921
- Comparative Effectiveness of Intravenous Tenecteplase versus Alteplase in Posterior Circulation Ischemic Stroke: A Systematic Review and Meta-AnalysisBrain Behav2026 OctPMID 42851038Meta-analysisSystematic reviewReview
- Door-to-Needle Optimization in Acute Ischemic Stroke: A Review of Rapid Emergency Department InterventionsCardiol Cardiovasc Med2026 OctPMID 42807530
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How these numbers are counted
PubMed query, searched in titles and abstracts by publication date:
tenecteplase[tiab] AND stroke[tiab]Trials: ClinicalTrials.gov studies first submitted in each 12-month window that match the same terms. A query can miss synonyms or catch unrelated papers, so treat counts as approximate.