Obesity medicines in adolescents
GLP-1 based medicines for obesity in children and adolescents.
Key point
Pharmacotherapy is recommended for adolescents aged 12 years and older as adjunct therapy when appropriate, alongside intensive health behavior and lifestyle treatment.
From: Pharmacotherapy in childhood obesity: Key points from the 2023 AAP clinical practice guideline (Semin Pediatr Surg, 2026 Jun) ↗Papers per year
Each bar is 12 months; the last one ends 17 Oct 2026. New trials in the same years: 29, 25, 33, 37, 50.
New guidelines and consensus this year
- Pharmacotherapy in childhood obesity: Key points from the 2023 AAP clinical practice guidelineSemin Pediatr Surg2026 Jun
- Swiss obesity clinical practice guidanceSwiss Med Wkly2026 May 19
All papers from the last 12 months
231 papers (18 Oct 2025 – 17 Oct 2026), newest first. Loading the full list…
- The pharmacotherapy for pediatric obesity: insights and challenges from adult weight-loss medicationsJ Diabetes Metab Disord2026 DecPMID 42871568Review
- Specialty-based variation in glucagon-like Peptide-1 receptor agonist prescribing practices for adolescent obesity in Saudi ArabiaObes Pillars2026 DecPMID 42733817
- Protecting Musculoskeletal Development and Physical Function in Adolescents on GLP-1 TherapyChild Obes2026 DecPMID 42544560Review
- GLP-1 receptor agonists in adolescent obesity: Incretin-based therapies during a sensitive developmental periodAppetite2026 Dec 1PMID 42508693Review
- Anti-obesity medications in children and adolescents: blood pressure and chronic kidney disease implicationsPediatr Nephrol2026 DecPMID 42033464Review
- Dulaglutide vs insulin in adolescents with thalassaemia-induced diabetes: effect on metabolism and atherogenesis (DIADEMA)Diabetologia2026 NovPMID 42618811RCT
- Real-world effectiveness of tirzepatide among youth with type 2 diabetes and/or obesity: a multicenter analysisJ Pediatr Endocrinol Metab2026 Oct 26PMID 42576608
- Obesity-Related Asthma: Structure and InflammationCurr Allergy Asthma Rep2026 Oct 14PMID 42873426Review
- Risk of recurrent acute pancreatitis with GLP-1 receptor agonists after prior pancreatitis: a systematic reviewActa Diabetol2026 Oct 14PMID 42873314Review
- Tirzepatide use in adolescents with metabolic dysfunction-associated steatotic liver disease (MASLD): A case seriesJPGN Rep2026 Oct 12PMID 42865987
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How these numbers are counted
PubMed query, searched in titles and abstracts by publication date:
(semaglutide[tiab] OR liraglutide[tiab] OR "GLP-1"[tiab] OR tirzepatide[tiab]) AND (adolescen*[tiab] OR child*[tiab] OR pediatric[tiab] OR paediatric[tiab])Trials: ClinicalTrials.gov studies first submitted in each 12-month window that match the same terms. A query can miss synonyms or catch unrelated papers, so treat counts as approximate.