Post-transplant cyclophosphamide
Cyclophosphamide after stem cell transplant to prevent graft-versus-host disease.
Key point
Post-transplant cyclophosphamide appears to reduce graft-versus-host disease without increasing relapse or mortality in matched related donor transplantation for acute leukemia.
From: Post-transplant cyclophosphamide as graft-versus-host disease prophylaxis for matched related donor hematopoietic stem cell transplantation in acute leukemia: a systematic review and meta-analysis (Hematology, 2026 Dec) ↗Papers per year
Each bar is 12 months; the last one ends 17 Oct 2026. New trials in the same years: 15, 20, 17, 22, 18.
New guidelines and consensus this year
All papers from the last 12 months
303 papers (18 Oct 2025 – 17 Oct 2026), newest first. Loading the full list…
- Cost-effectiveness of Orca-T vs allo-HCT with conventional GVHD prophylaxis for the treatment of advanced hematologic malignancies in the United StatesJ Med Econ2026 DecPMID 42806776
- Post-transplant cyclophosphamide as graft-versus-host disease prophylaxis for matched related donor hematopoietic stem cell transplantation in acute leukemia: a systematic review and meta-analysisHematology2026 DecPMID 41770801Meta-analysisSystematic review
- Haploidentical transplantation versus umbilical cord blood transplantation in acute myeloid leukemia with measurable residual diseaseCytotherapy2026 NovPMID 42679593
- Phase II Study of Posttransplant Cyclophosphamide-Based Graft-Versus-Host Disease Prophylaxis After HLA-Mismatched Unrelated Donor Reduced Intensity Transplantation: Results From the ACCESS Trial Expansion CohortAm J Hematol2026 NovPMID 42674730
- Mitigating HLA Disparity in AML Transplantation: Comparable Outcomes After Haploidentical and 9/10 Mismatched Unrelated Donor Transplantation With Treosulfan and PTCyAm J Hematol2026 NovPMID 42631537
- Erratum: Post-Transplant Cyclophosphamide-Based Graft-Versus-Host Disease Prophylaxis After Mismatched Unrelated Donor Peripheral Blood Stem Cell TransplantationJ Clin Oncol2026 Oct 20PMID 42748388
- Does Less Than 100 mg/kg Necessarily Represent Reduced Post-Transplant Cyclophosphamide Exposure?Transplant Cell Ther2026 Oct 16PMID 42887727
- External Validation of the CARE-BMT and Modified CARE-BMT Scores for Cardiac Event Prediction After Allogeneic Hematopoietic Cell Transplantation in Acute Myeloid LeukemiaTransplant Cell Ther2026 Oct 16PMID 42887726
- Does Lower PTCy Dose Increase GVHD?Transplant Cell Ther2026 Oct 15PMID 42880544
- Early measurement of ST2 and REG3α has a prognostic impact in haploidentical transplantation with post-transplant cyclophosphamideHaematologica2026 Oct 15PMID 42876307
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How these numbers are counted
PubMed query, searched in titles and abstracts by publication date:
"post-transplant cyclophosphamide"[tiab] OR PTCy[tiab]Trials: ClinicalTrials.gov studies first submitted in each 12-month window that match the same terms. A query can miss synonyms or catch unrelated papers, so treat counts as approximate.