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All nephrology trends
EmergingNephrology · updated 18 Oct 2026

Potassium binders

Patiromer and sodium zirconium cyclosilicate for hyperkalaemia.

Key point

In type 2 diabetes with hyperkalemia, sodium zirconium cyclosilicate did not demonstrate noninferiority to potassium-restricted diet for achieving normokalemia.

From: Sodium zirconium cyclosilicate compared with potassium restriction for hyperkalemia management in type 2 diabetes: The SILVERSTAR trial (J Diabetes Investig, 2026 Sep) ↗
7PubDaily Trend Score
-20%new papers vs last year
2new trials registered
0new guidelines this year

Papers per year

Each bar is 12 months; the last one ends 17 Oct 2026. New trials in the same years: 5, 4, 6, 3, 2.

All papers from the last 12 months

60 papers (18 Oct 2025 – 17 Oct 2026), newest first. Loading the full list…

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  1. Navigating the data-scarce landscape of pediatric hyperkalemia: a perspective on sodium zirconium cyclosilicate
    Pediatr Nephrol2026 DecPMID 42059926Review
  2. The Unfulfilled Promise of Potassium Binding in Heart Failure With Reduced Ejection Fraction
    J Am Coll Cardiol2026 Oct 13PMID 42615956
  3. Sustained potassium control and recurrent hyperkalemia during individualized potassium-guided sodium zirconium cyclosilicate titration in maintenance hemodialysis: a post hoc analysis of a randomized trial
    BMC Nephrol2026 Oct 12PMID 42875751RCT
  4. Ionic immune checkpoint blockade through potassium-scavenging hydrogel to potentiate CD8(+) T cell-mediated cancer immunotherapy
    Biomaterials2026 OctPMID 41999708
  5. Overcoming Hyperkalaemia to Optimise Heart Failure Therapy: The Emerging Role of Novel Potassium Binders
    Card Fail Rev2026PMID 42866084Review
  6. Letter to the Editor: Enhancing renin-angiotensin-aldosterone system inhibitors utilization through patiromer adherence - real-world insights for nephrology practice
    World J Nephrol2026 Sep 25PMID 42626019
  7. Beyond potassium lowering: interpreting an adaptive sodium zirconium cyclosilicate strategy in hemodialysis
    Int Urol Nephrol2026 Sep 9PMID 42714792
  8. Sodium zirconium cyclosilicate compared with potassium restriction for hyperkalemia management in type 2 diabetes: The SILVERSTAR trial
    J Diabetes Investig2026 SepPMID 42423524RCT
  9. The Endoscopic Removal of a Gastric Bezoar Made of Sodium Zirconium Cyclosilicate Hydrate
    Intern Med2026 Sep 1PMID 41535045
  10. Post-marketing safety associated with sodium zirconium cyclosilicate: a pharmacovigilance study based on the FDA reporting system
    Expert Opin Drug Saf2026 SepPMID 40151141

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How these numbers are counted

PubMed query, searched in titles and abstracts by publication date:

patiromer[tiab] OR "sodium zirconium cyclosilicate"[tiab]

Trials: ClinicalTrials.gov studies first submitted in each 12-month window that match the same terms. A query can miss synonyms or catch unrelated papers, so treat counts as approximate.