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All nephrology trends
RisingNephrology · updated 18 Oct 2026

Acute kidney injury biomarkers

Biomarkers to detect and predict acute kidney injury.

70PubDaily Trend Score
+26%new papers vs last year
104new trials registered
2new guidelines this year

Papers per year

Each bar is 12 months; the last one ends 17 Oct 2026. New trials in the same years: 49, 52, 59, 68, 104.

New guidelines and consensus this year

  1. Kidney disease and heart failure: recent advances and current challenges: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference
    Kidney Int2026 Jun
  2. Kidney Disease and Heart Failure: Recent Advances and Current Challenges: Conclusions From a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference
    JACC Heart Fail2026 Apr

All papers from the last 12 months

910 papers (18 Oct 2025 – 17 Oct 2026), newest first. Loading the full list…

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  1. Electrochemical immunosensors for KIM-1 and NGAL: recent advances toward early and point-of-care diagnosis of acute kidney injury
    Clin Chim Acta2027 Feb 15PMID 42679883Review
  2. Diagnostic pitfall: NSAID-induced membranous nephropathy with PLA2R positivity, IgG1-predominant deposits, C1q positivity, and concurrent acute interstitial nephritis-A case report
    Clin Chim Acta2027 Feb 15PMID 42503368
  3. Lactate in acute kidney injury: pathobiology, risk stratification, and clinical interpretation
    Ren Fail2026 DecPMID 42802082Review
  4. Occupational heatstroke-induced acute kidney injury: a narrative review of mechanisms, biomarkers, and the timing of blood purification initiation
    Ren Fail2026 DecPMID 42734065Review
  5. Diagnostic and prognostic value of fibroblast growth factor 23 in acute kidney injury: systematic review and meta-analysis
    Ren Fail2026 DecPMID 42693098Meta-analysisSystematic review
  6. Integrated biomarker analysis of multi-organ effects following MDMA and alcohol co-consumption in Pakistan: A pilot study
    Toxicol Rep2026 DecPMID 42620295
  7. Association of transglutaminase-2 with contrast-induced acute kidney injury in Chinese patients with acute coronary syndrome: a prospective cohort study
    Ann Med2026 DecPMID 42573605
  8. Novel biomarkers for acute kidney injury in high-risk pediatric populations: a systematic review
    Ren Fail2026 DecPMID 42448446Systematic review
  9. Urinary neutrophil gelatinase-associated lipocalin: a key biomarker for differentiating acute kidney injury and predicting short-term mortality in liver cirrhosis patients
    Ren Fail2026 DecPMID 42409784
  10. A four-gene signature for diagnosis of acute kidney injury following kidney transplantation
    Ren Fail2026 DecPMID 42315974

More nephrology trends

All specialties →

GLP-1 drugs in kidney disease

Rising fast
+48%new papersScore 81
20212026

GLP-1 based medicines and kidney outcomes.

Key point: In CKD, GLP-1 receptor agonists were associated with fewer major adverse kidney events and lower albuminuria, primarily in type 2 diabetes, with gastrointestinal concerns.

371 papers / yr30 new trials2 new guidelines
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SGLT2 inhibitors in CKD

Rising
+41%new papersScore 72
20212026

SGLT2 inhibitors to slow chronic kidney disease.

Key point: In non-diabetic CKD, renin-angiotensin system inhibitors and SGLT2 inhibitors would be indicated as the treatment of choice.

712 papers / yr52 new trials2 new guidelines
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IgA nephropathy

Rising
+33%new papersScore 68
20212026

IgA nephropathy and the new targeted treatments being studied.

889 papers / yr47 new trials1 new guideline
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Lupus nephritis

Rising
+18%new papersScore 61
20212026

Kidney involvement in lupus and its newer treatments.

Key point: Lupus nephritis management is increasingly individualized, with expanding treatment options, combination therapy, and a trend toward lower corticosteroid doses.

1,129 papers / yr53 new trials6 new guidelines
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Complement inhibitors in kidney disease

Steady
+38%new papersScore 44
20212026

Iptacopan, avacopan and other complement inhibitors in glomerular disease.

Key point: Complement inhibitors had no overall effectiveness or safety advantage over plasma therapy in atypical hemolytic uremic syndrome, except lower relapse rates.

209 papers / yr6 new trials1 new guideline
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APOL1 kidney disease

Steady
+5%new papersScore 40
20212026

Kidney disease linked to APOL1 gene variants.

127 papers / yr1 new trials1 new guideline
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How these numbers are counted

PubMed query, searched in titles and abstracts by publication date:

"acute kidney injury"[tiab] AND biomarker*[tiab]

Trials: ClinicalTrials.gov studies first submitted in each 12-month window that match the same terms. A query can miss synonyms or catch unrelated papers, so treat counts as approximate.