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All nephrology trends
RisingNephrology · updated 18 Oct 2026

IgA nephropathy

IgA nephropathy and the new targeted treatments being studied.

68PubDaily Trend Score
+33%new papers vs last year
47new trials registered
1new guidelines this year

Papers per year

Each bar is 12 months; the last one ends 17 Oct 2026. New trials in the same years: 21, 18, 18, 47, 47.

New guidelines and consensus this year

  1. KDOQI US Commentary on the KDIGO 2025 Clinical Practice Guideline for the Management of Immunoglobulin A Nephropathy (IgAN) and Immunoglobulin A Vasculitis (IgAV)
    Am J Kidney Dis2026 Jul

All papers from the last 12 months

889 papers (18 Oct 2025 – 17 Oct 2026), newest first. Loading the full list…

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  1. A self-powered sensor with cascade signal amplification strategy based on CuS@Au heterojunctions/Ti(3)C(2) MXene for detection of IgAN urinary miRNA-23b-3p
    Talanta2027 Feb 1PMID 42623826
  2. Multi-omics body-fluid biomarkers in immunoglobulin a nephropathy: Analytical Validation, standardization, and clinical chemistry translation of diagnostic and prognostic Analytes
    Clin Chim Acta2027 Jan 1PMID 42297320Review
  3. The shared mechanisms and potential diagnostic markers for IgA nephropathy and celiac disease
    Autoimmunity2026 Dec 31PMID 41714845
  4. Clinical and pathological factors associated with eGFR slope in IgA nephropathy: a single-center retrospective cohort study
    Ren Fail2026 DecPMID 42844235
  5. Artificial intelligence-powered renal pathology for glomerular disease classification: a systematic review and meta-analysis
    Ren Fail2026 DecPMID 42838512Meta-analysisSystematic review
  6. Microplastics and IgA nephropathy: a novel environmental hypothesis of immune dysregulation
    Ren Fail2026 DecPMID 42817229Review
  7. Smoking exposure and long-term progression of IgA nephropathy: a retrospective cohort study of 9,560 patients
    Ren Fail2026 DecPMID 42786735
  8. Clinical characteristics and prognosis of IgA nephropathy and comorbid diabetic kidney disease
    Ann Med2026 DecPMID 42714219
  9. Kidney biopsy in patients with small kidneys: diagnostic yield and treatment modification in a retrospective cohort study
    Ren Fail2026 DecPMID 42687510
  10. Efficacy and safety of finerenone in adults with IgA nephropathy: a 12-month real-world study
    Ren Fail2026 DecPMID 42634326

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GLP-1 drugs in kidney disease

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+48%new papersScore 81
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GLP-1 based medicines and kidney outcomes.

Key point: In CKD, GLP-1 receptor agonists were associated with fewer major adverse kidney events and lower albuminuria, primarily in type 2 diabetes, with gastrointestinal concerns.

371 papers / yr30 new trials2 new guidelines
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SGLT2 inhibitors in CKD

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+41%new papersScore 72
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SGLT2 inhibitors to slow chronic kidney disease.

Key point: In non-diabetic CKD, renin-angiotensin system inhibitors and SGLT2 inhibitors would be indicated as the treatment of choice.

712 papers / yr52 new trials2 new guidelines
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Acute kidney injury biomarkers

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+26%new papersScore 70
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Biomarkers to detect and predict acute kidney injury.

910 papers / yr104 new trials2 new guidelines
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Lupus nephritis

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+18%new papersScore 61
20212026

Kidney involvement in lupus and its newer treatments.

Key point: Lupus nephritis management is increasingly individualized, with expanding treatment options, combination therapy, and a trend toward lower corticosteroid doses.

1,129 papers / yr53 new trials6 new guidelines
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Complement inhibitors in kidney disease

Steady
+38%new papersScore 44
20212026

Iptacopan, avacopan and other complement inhibitors in glomerular disease.

Key point: Complement inhibitors had no overall effectiveness or safety advantage over plasma therapy in atypical hemolytic uremic syndrome, except lower relapse rates.

209 papers / yr6 new trials1 new guideline
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APOL1 kidney disease

Steady
+5%new papersScore 40
20212026

Kidney disease linked to APOL1 gene variants.

127 papers / yr1 new trials1 new guideline
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How these numbers are counted

PubMed query, searched in titles and abstracts by publication date:

"IgA nephropathy"[tiab]

Trials: ClinicalTrials.gov studies first submitted in each 12-month window that match the same terms. A query can miss synonyms or catch unrelated papers, so treat counts as approximate.