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All gastroenterology trends
RisingGastroenterology · updated 18 Oct 2026

Fecal microbiota transplantation

Transferring stool microbiota to treat C. difficile and other conditions.

Key point

Fecal microbiota-based therapies should be offered after treatment of a second recurrence of Clostridioides difficile infection.

From: AGA Clinical Practice Update on Management of Clostridioides difficile Infection in Adults: Expert Review (Clin Gastroenterol Hepatol, 2026 Sep) ↗
71PubDaily Trend Score
+31%new papers vs last year
72new trials registered
4new guidelines this year

Papers per year

Each bar is 12 months; the last one ends 17 Oct 2026. New trials in the same years: 45, 66, 69, 48, 72.

New guidelines and consensus this year

  1. AGA Clinical Practice Update on Management of Clostridioides difficile Infection in Adults: Expert Review
    Clin Gastroenterol Hepatol2026 Sep
  2. AGA Clinical Practice Update on Management of Clostridioides difficile Infection in Inflammatory Bowel Disease: Expert Review
    Gastroenterology2026 Jul
  3. [Acute graft-versus-host disease therapy: Which third line treatment after steroids and ruxolitinib? (SFGM-TC)]
    Bull Cancer2026 Jun
  4. Clostridioides difficile infection: Position paper of the Catalan Society of Gastroenterology
    Gastroenterol Hepatol2026 May

All papers from the last 12 months

2,255 papers (18 Oct 2025 – 17 Oct 2026), newest first. Loading the full list…

Open this search in PubMed
  1. Water-responsive injectable hydrogel achieving rapid in situ gelation and long-term colonic mucoadhesion for efficient fecal microbiota transplantation
    Bioact Mater2027 FebPMID 42733554
  2. Mechanistic insights into Cistanche deserticola aqueous extract in alleviating functional constipation: Integration of gut microbiota remodeling and focal adhesion-associated mucosal repair
    J Ethnopharmacol2027 Jan 10PMID 42501925
  3. Da-Jian-Zhong decoction restores the gut-brain balance in diarrhea-predominant irritable bowel syndrome rats via gut microbiota-bile acid axis
    J Ethnopharmacol2027 Jan 10PMID 42498089
  4. Callistephus A from Callistephus chinensis alleviates DSS-induced ulcerative colitis and gut-liver axis disruption by targeting the JAK2/STAT1 pathway and remodeling gut microbiota
    J Ethnopharmacol2027 Jan 10PMID 42476206
  5. Probiotics alleviate heat stress-induced uterine inflammation, reproductive hormone disruption and fetal growth restriction in mice
    Theriogenology2027 Jan 1PMID 42753368
  6. Gut microbiota on sleep disorders throughout the lifespan
    Microbiol Res2027 JanPMID 42735570Review
  7. Rectal ozone insufflation modulates gut microbiota: improving lung function in mice with chronic obstructive pulmonary disease
    Med Gas Res2027 Jan 1PMID 42734449
  8. Xiaoyao San exerts antidepressant effects via the gut microbiota-brain axis: An integrative fMRI and multiomics study
    J Pharm Biomed Anal2027 Jan 1PMID 42580208
  9. Schizophrenia-associated gut microbiota are linked to reduced colonic PRODH expression and behavioral changes in mice
    Gut Microbes2026 Dec 31PMID 42886170
  10. Phytosterol-induced modulation of gut microbial bile salt hydrolases ameliorates hyperlipidemia via taurohyodeoxycholic acid-mediated FXR antagonism
    Gut Microbes2026 Dec 31PMID 42752278

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How these numbers are counted

PubMed query, searched in titles and abstracts by publication date:

"fecal microbiota transplant*"[tiab] OR "faecal microbiota transplant*"[tiab]

Trials: ClinicalTrials.gov studies first submitted in each 12-month window that match the same terms. A query can miss synonyms or catch unrelated papers, so treat counts as approximate.