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All gastroenterology trends
RisingGastroenterology · updated 18 Oct 2026

MASLD and MASH

Metabolic dysfunction-associated steatotic liver disease and its new treatments.

78PubDaily Trend Score
+34%new papers vs last year
177new trials registered
22new guidelines this year

Papers per year

Each bar is 12 months; the last one ends 17 Oct 2026. New trials in the same years: 12, 14, 84, 124, 177.

New guidelines and consensus this year

  1. Splanchnic Vein Thrombosis after Metabolic and Bariatric Surgery: Chilean Position Statement of Hepatology and Bariatric Surgery societies
    Obes Surg2026 Sep 23
  2. AGA Clinical Practice Update on the Evaluation and Management of Metabolic Dysfunction- and Alcohol-Associated Liver Disease: Expert Review
    Clin Gastroenterol Hepatol2026 Sep 22
  3. Colorectal cancer in metabolic dysfunction-associated steatotic liver disease: an international Delphi consensus statement
    Gut2026 Sep 7
  4. Consensus statement on obesity management in liver transplantation candidates
    Updates Surg2026 Sep
  5. Prevention, surveillance, and early detection of hepatocellular carcinoma - a Brazilian multidisciplinary consensus
    Arq Bras Cir Dig2026

All papers from the last 12 months

6,624 papers (18 Oct 2025 – 17 Oct 2026), newest first. Loading the full list…

Open this search in PubMed
  1. Gut microbiota and metabolic characteristics in PWHIV with metabolic dysfunction-associated steatotic liver disease (MASLD)
    Virulence2027 DecPMID 42834659
  2. Recent Development of Endo-hepatology
    DEN Open2027 AprPMID 42602295Review
  3. Targeted inhibition of inflammatory liver macrophages with a multifunctional nanoparticle ameliorates metabolic dysfunction-associated steatohepatitis
    Bioact Mater2027 MarPMID 42835072
  4. Bioactive glasses-mediated ion therapy ameliorates hepatic osteodystrophy by reprogramming the liver-bone axis
    Bioact Mater2027 FebPMID 42729454
  5. Babaodan ameliorates metabolic dysfunction-associated steatotic liver disease with co-modulation of FXR, NF-κB, and SLC22A7 in bile acid metabolism
    J Ethnopharmacol2027 Jan 10PMID 42472598
  6. Optimal dose window, formulation efficacy, and molecular mechanisms of curcumin in MASLD animal models: A systematic review and three-level meta-analysis
    J Ethnopharmacol2027 Jan 10PMID 42447971Meta-analysisSystematic review
  7. Gut microbiota shaping fatty liver disease progression
    Life Sci Alliance2027 JanPMID 42864263Review
  8. Integrating Cardiovascular Risk Assessment into Metabolic Dysfunction-associated Steatotic Liver Disease Drug Development
    J Clin Exp Hepatol2027 Jan-FebPMID 42857154
  9. Imeglimin provides dual hepatic and skeletal muscle protection in experimental MASH-associated sarcopenia
    Biochim Biophys Acta Mol Basis Dis2027 JanPMID 42759777
  10. Sinusoidal endothelial cells orchestrate liver inflammation and lipid metabolism via USP12/CD36 axis being the target of celastrol therapy
    Biochim Biophys Acta Mol Basis Dis2027 JanPMID 42710599

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How these numbers are counted

PubMed query, searched in titles and abstracts by publication date:

MASLD[tiab] OR MASH[tiab] OR "metabolic dysfunction-associated steatotic"[tiab] OR resmetirom[tiab]

Trials: ClinicalTrials.gov studies first submitted in each 12-month window that match the same terms. A query can miss synonyms or catch unrelated papers, so treat counts as approximate.