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Research trends

What gastroenterology is researching now

The topics gaining the most ground, ranked by the PubDaily Trend Score: new research, stronger evidence, new trials and new guidelines. 291 topics in 22 specialties, updated 18 Oct 2026.

Monthly reportThe fastest-rising topics in medicine: October 2026Read →
13 topics · gastroenterology

MASLD and MASH

Rising
+34%new papersScore 78
20212026

Metabolic dysfunction-associated steatotic liver disease and its new treatments.

6,624 papers / yr177 new trials22 new guidelines
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Fecal microbiota transplantation

Rising
+31%new papersScore 71
20212026

Transferring stool microbiota to treat C. difficile and other conditions.

Key point: Fecal microbiota-based therapies should be offered after treatment of a second recurrence of Clostridioides difficile infection.

2,255 papers / yr72 new trials4 new guidelines
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IL-23 inhibitors in IBD

Rising
+30%new papersScore 61
20212026

Risankizumab, mirikizumab and guselkumab in Crohn's disease and ulcerative colitis.

214 papers / yr35 new trials4 new guidelines
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EUS-guided interventions

Rising
+18%new papersScore 60
20212026

Therapeutic procedures guided by endoscopic ultrasound.

1,222 papers / yr61 new trials1 new guideline
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Endoscopic bariatric therapy

Rising
+27%new papersScore 57
20212026

Endoscopic sleeve gastroplasty and other endoscopic weight-loss procedures.

132 papers / yr11 new trials2 new guidelines
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Early-onset colorectal cancer

Rising
+29%new papersScore 56
20212026

Colorectal cancer in adults under 50.

340 papers / yr8 new trials
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See all 13 gastroenterology topics

Every rising topic, with the papers behind it. Free for doctors.

How the Trend Score works

Four signals

Growth in new papers (35%), growth in randomised trials, meta-analyses and systematic reviews (25%), new clinical trials registered (20%), and new guidelines and consensus statements (20%), each over the last 12 months against the 12 before.

A score out of 100

Each signal is ranked against every topic we follow, so a score of 90 means the topic is ahead of about 90% of them. Rising fast: 80 and above. Rising: 55 to 79. Emerging: fewer than 100 papers the year before, too few to rank.

What it does not tell you

More research on a topic is not evidence that a treatment works. Open a topic to read the papers and guidelines themselves. Counts come from PubMed and ClinicalTrials.gov.