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All infectious diseases trends
RisingInfectious diseases · updated 18 Oct 2026

Long-acting HIV prevention

Lenacapavir and cabotegravir injections for HIV pre-exposure prophylaxis.

67PubDaily Trend Score
+29%new papers vs last year
37new trials registered
1new guidelines this year

Papers per year

Each bar is 12 months; the last one ends 17 Oct 2026. New trials in the same years: 18, 27, 39, 24, 37.

New guidelines and consensus this year

  1. Canadian guideline on HIV pre- and postexposure prophylaxis: 2025 update
    CMAJ2025 Nov 30

All papers from the last 12 months

543 papers (18 Oct 2025 – 17 Oct 2026), newest first. Loading the full list…

Open this search in PubMed
  1. Analytical description of adverse events with long-acting injectable cabotegravir and rilpivirine in people living with HIV: a large multicentre prospective observational cohort study (SCOLTA)
    HIV Res Clin Pract2026 Dec 31PMID 42765669
  2. Italy is ready-extended PrEP cascade, and determinants of intention to use long-acting PrEP and unmet PrEP needs among men who have sex with men, trans* individuals, heterosexual women, and men
    HIV Res Clin Pract2026 Dec 31PMID 42186205
  3. Successful initiation of fully parenteral antiretroviral therapy in a treatment-naïve person with HIV-1 infection and intestinal failure
    HIV Res Clin Pract2026 Dec 31PMID 41964115
  4. Investing in enhanced HIV prevention among young men who have sex with men in Brazil: insights from fiscal health modeling
    J Med Econ2026 DecPMID 42543243
  5. Persistent injection-site nodules visible on cross-sectional imaging: clinical experience with injectable lenacapavir and review of the literature
    AIDS2026 Nov 1PMID 42826229
  6. Tolerability and Virologic Outcomes after Transition from Long-Acting Injectable ART to Oral ART
    AIDS Patient Care STDS2026 NovPMID 42728773
  7. Narrative Review of Two-Drug Regimens in Modern HIV Care: Driving Innovation, Flexibility, and Quality of Life
    Infect Dis Ther2026 NovPMID 42728470Review
  8. Cabotegravir and rilpivirine resistance-associated mutations among people with newly diagnosed HIV-1 in the Netherlands
    AIDS2026 Nov 1PMID 42357947
  9. Numerous linked cases of acute genotype F hepatitis B virus infections in people living with HIV or on pre-exposure prophylaxis
    Clin Microbiol Infect2026 Oct 16PMID 42887637
  10. Methodological considerations for indirect treatment comparisons of HIV incidence for long-acting injectable pre-exposure prophylaxis
    J Comp Eff Res2026 Oct 15PMID 42878002Review

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How these numbers are counted

PubMed query, searched in titles and abstracts by publication date:

lenacapavir[tiab] OR cabotegravir[tiab] OR ("pre-exposure prophylaxis"[tiab] AND "long-acting"[tiab])

Trials: ClinicalTrials.gov studies first submitted in each 12-month window that match the same terms. A query can miss synonyms or catch unrelated papers, so treat counts as approximate.