Metagenomic sequencing diagnostics
Metagenomic next-generation sequencing to identify pathogens.
Papers per year
Each bar is 12 months; the last one ends 17 Oct 2026. New trials in the same years: 19, 21, 17, 19, 27.
All papers from the last 12 months
1,078 papers (18 Oct 2025 – 17 Oct 2026), newest first. Loading the full list…
- Diagnostic value of metagenomic next-generation sequencing for bacterial and fungal detection and its role in antimicrobial therapy adjustment in critically ill patients with non-resolving pneumoniaAnn Med2026 DecPMID 42806854
- Immune-guided calibration of metagenomic next-generation sequencing (mNGS) results in a pregnant patient with Listeria infection: a case reportJ Matern Fetal Neonatal Med2026 DecPMID 42472698
- Granulomatous inflammation in lung and lymph node specimens: A molecularly enhanced pathology-based algorithm for etiologic differential diagnosisAnn Diagn Pathol2026 DecPMID 42442149Review
- Molecular evidence of neuroinvasive Sindbis virus infection in humans: detection in cerebrospinal fluid by next generation sequencingEmerg Microbes Infect2026 DecPMID 42434987
- Avian paramyxovirus type 1-associated severe pneumonia in humans: Molecular characterization and zoonotic transmission riskOne Health2026 DecPMID 42388836
- Metagenomic next-generation sequencing for pathology-suspected fungal infections at rare anatomical sites: a case seriesFuture Sci OA2026 DecPMID 42100992
- Clinical, laboratory, and radiological features of community-acquired pneumonia due to Chlamydia psittaci and Legionella pneumophila confirmed using next-generation sequencingAnn Med2026 DecPMID 41684123
- Letter to the editor regarding: 'Diagnostic value of plasma cell-free DNA metagenomic next-generation sequencing in patients with suspected infections and exploration of clinical scenarios - a retrospective study from a single center'Ann Med2026 DecPMID 41653157
- Congenital babesiosis in China: first molecularly confirmed case of vertical transmission of Babesia microtiEmerg Microbes Infect2026 DecPMID 41559018
- Diagnostic value of plasma cell-free DNA metagenomic next-generation sequencing in patients with suspected infections and exploration of clinical scenarios-a retrospective study from a single centerAnn Med2026 DecPMID 41481221
More infectious diseases trends
All specialties →Shorter antibiotic courses
Shorter durations of antibiotic therapy.
Key point: For children with acute uncomplicated UTIs, shorter-course antibiotic therapy appears comparable with longer-course therapy in efficacy and safety.
Long-acting HIV prevention
Lenacapavir and cabotegravir injections for HIV pre-exposure prophylaxis.
Candida auris
A multidrug-resistant fungus spreading in healthcare settings.
RSV vaccines in older adults
RSV vaccination for adults aged 60 and older.
New antibiotics for resistant Gram-negatives
Cefiderocol, sulbactam-durlobactam and other new agents.
Shorter regimens for tuberculosis
Bedaquiline, pretomanid and other shorter TB regimens.
Key point: For adolescents aged 14 years and above and adults with MDR/RR-TB, 6-month BPaLM is recommended over 9-month or longer regimens.
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How these numbers are counted
PubMed query, searched in titles and abstracts by publication date:
"metagenomic next-generation sequencing"[tiab] OR mNGS[tiab]Trials: ClinicalTrials.gov studies first submitted in each 12-month window that match the same terms. A query can miss synonyms or catch unrelated papers, so treat counts as approximate.