MDMA-assisted therapy
MDMA combined with psychotherapy, mainly studied in PTSD.
Papers per year
Each bar is 12 months; the last one ends 17 Oct 2026. New trials in the same years: 8, 11, 4, 4, 6.
New guidelines and consensus this year
All papers from the last 12 months
133 papers (18 Oct 2025 – 17 Oct 2026), newest first. Loading the full list…
- The Nova Protocol: a comprehensive multimodal longitudinal study among civilian survivors of a mass trauma eventEur J Psychotraumatol2026 DecPMID 42735067
- A neurocognitive account of complex PTSD: self-modelling, affective dysregulation, and implications for MDMA-assisted and targeted psychotherapiesEur J Psychotraumatol2026 DecPMID 41853928Review
- The microbiome and PTSD: a scoping review across preclinical and clinical studiesEur J Psychotraumatol2026 DecPMID 41790992
- α(2)-Adrenergic receptor modulates 5-HT(2A)-mediated behavioral effects of MDMA and psilocybin in miceMol Psychiatry2026 NovPMID 42414551
- A living systematic review, meta-analysis, and open data resource of trials of MDMA-assisted therapy for PTSDNeuropsychopharmacology2026 Oct 11PMID 42860436
- Population-Stratified Distributions of Post-Mortem Blood Drug Concentrations: An Epidemiological Framework for Contextual InterpretationDrug Test Anal2026 Oct 6PMID 42839309
- Acute cardiovascular complications of sympathomimetic recreational drug useClin Toxicol (Phila)2026 OctPMID 42504704Review
- MDMA and Psilocybin Regulate Oligodendrocyte-Lineage Cell Numbers and Anxiety-Like Behaviors in a Rat Model of FearBiol Psychiatry2026 Sep 15PMID 41644029
- Implications of Potential US FDA Approval of Psychedelics or Psychedelic-Adjacents Such as Ibogaine for Pharmacy in JapanCureus2026 SepPMID 42733721Review
- [The use of psychedelics in psychiatry]Orv Hetil2026 Sep 13PMID 42732542Review
More psychiatry trends
All specialties →Gut microbiome and mental health
Links between the gut microbiome and depression or anxiety.
Psilocybin therapy
Psilocybin-assisted therapy for depression and other conditions.
Brain stimulation for depression
Transcranial magnetic stimulation, including accelerated theta-burst protocols, for depression.
Key point: Connectivity- or frequency- and connectivity-individualized accelerated iTBS failed to yield significant antidepressant benefits over sham stimulation in treatment-resistant depression.
Ketamine and esketamine for depression
Ketamine and esketamine for treatment-resistant depression.
Muscarinic antipsychotics
Xanomeline-trospium and other muscarinic drugs for schizophrenia.
Neurosteroids for postpartum depression
Zuranolone and brexanolone for postpartum depression.
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How these numbers are counted
PubMed query, searched in titles and abstracts by publication date:
MDMA[tiab] AND (therap*[tiab] OR PTSD[tiab])Trials: ClinicalTrials.gov studies first submitted in each 12-month window that match the same terms. A query can miss synonyms or catch unrelated papers, so treat counts as approximate.