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All ophthalmology trends
SteadyOphthalmology · updated 18 Oct 2026

AI in retinal imaging

Deep learning on fundus photos and OCT, including signs of systemic disease.

51PubDaily Trend Score
+18%new papers vs last year
42new trials registered
2new guidelines this year

Papers per year

Each bar is 12 months; the last one ends 17 Oct 2026. New trials in the same years: 17, 31, 28, 41, 42.

New guidelines and consensus this year

  1. Special AAO Report: Recommendations on Screening for Hydroxychloroquine Retinopathy (2025 Revision)
    Ophthalmology2026 Apr
  2. International Consensuses and Guidelines on Diagnosing and Managing Coats Disease by the Academia Retina Internationalis (ARI), the Asia-Pacific Vitreo-retina Society (APVRS), and the Academy of the Asia-Pacific Professors of Ophthalmology (AAPPO)
    Am J Ophthalmol2026 Feb

All papers from the last 12 months

1,425 papers (18 Oct 2025 – 17 Oct 2026), newest first. Loading the full list…

Open this search in PubMed
  1. Multi-modal deep learning for non-invasive blood glucose prediction from terahertz reflection spectra: A simulation study with four-layer skin modeling
    Spectrochim Acta A Mol Biomol Spectrosc2026 Dec 15PMID 42468391
  2. Retinal image analysis for clinical translation: From deep learning to foundation models, generalization, and trustworthy deployment
    Artif Intell Med2026 DecPMID 42785152Review
  3. Beyond the field of view: Radiomics and artificial intelligence for organ-specific and systemic disease prediction from localized medical imaging
    Artif Intell Med2026 DecPMID 42748665Review
  4. DMNet-E: Enhanced dual-segmentation multi-decoder network strategy for advancing IVOCT plaque segmentation
    Artif Intell Med2026 DecPMID 42735616
  5. Using the Normalization Process Theory to study facilitators and barriers to sustainable implementation of artificial intelligence-based diabetic retinopathy screening in Rwanda
    Dialogues Health2026 DecPMID 42569249
  6. From annotation to analysis: a deep-learning pipeline for optical coherence tomography (OCT)-based measurements of biofilm morphology
    Biofilm2026 DecPMID 42518799
  7. A hybrid CNN-GNN and multitask learning pipeline for improving mild diabetic retinopathy sensitivity
    MethodsX2026 DecPMID 42436968
  8. Hybrid deep learning models for diabetic retinopathy stage classification using fundus images
    J Diabetes Metab Disord2026 DecPMID 42381712
  9. Retinal vascular parameters as AI-driven biomarkers for pulse wave velocity assessment: a telemedicine strategy for cardiovascular risk assessment
    Ann Med2026 DecPMID 42360005
  10. The diagnostic accuracy of AI-assisted diabetic retinopathy screening in primary care: a prospective validation study
    Scand J Prim Health Care2026 DecPMID 42284159

More ophthalmology trends

All specialties →

Longer-acting anti-VEGF

Rising
+55%new papersScore 64
20212026

Faricimab and high-dose aflibercept for retinal disease.

428 papers / yr26 new trials
See all papers →

Myopia control in children

Rising
+19%new papersScore 57
20212026

Atropine drops, defocus lenses and orthokeratology to slow myopia.

Key point: In myopic children, atropine efficacy increased nonlinearly with concentration and may plateau, while higher doses were associated with decreased accommodation and photophobia.

567 papers / yr79 new trials1 new guideline
See all papers →

Ischaemic optic neuropathy

Steady
-1%new papersScore 52
20212026

Non-arteritic anterior ischaemic optic neuropathy, including reports linked to GLP-1 drugs.

Key point: In acute NAION, increased early optic nerve head swelling rates were associated with visual field and visual acuity worsening by month 6.

403 papers / yr7 new trials2 new guidelines
See all papers →

Diabetic retinopathy screening

Steady
+20%new papersScore 48
20212026

Screening for diabetic retinopathy, including autonomous AI.

522 papers / yr24 new trials1 new guideline
See all papers →

Gene therapy for inherited retinal disease

Steady
+16%new papersScore 41
20212026

Gene therapy and optogenetics for inherited retinal dystrophies.

181 papers / yr6 new trials
See all papers →

Minimally invasive glaucoma surgery

Steady
+13%new papersScore 37
20212026

MIGS devices and procedures.

Key point: Phaco-iStent and phaco-KDB both significantly reduced intraocular pressure and glaucoma medication burden with few postoperative complications.

278 papers / yr7 new trials
See all papers →

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How these numbers are counted

PubMed query, searched in titles and abstracts by publication date:

("artificial intelligence"[tiab] OR "deep learning"[tiab]) AND (retina*[tiab] OR fundus[tiab] OR "optical coherence tomography"[tiab])

Trials: ClinicalTrials.gov studies first submitted in each 12-month window that match the same terms. A query can miss synonyms or catch unrelated papers, so treat counts as approximate.