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Research trends

What ophthalmology is researching now

The topics gaining the most ground, ranked by the PubDaily Trend Score: new research, stronger evidence, new trials and new guidelines. 291 topics in 22 specialties, updated 18 Oct 2026.

Monthly reportThe fastest-rising topics in medicine: October 2026Read →
12 topics · ophthalmology

Longer-acting anti-VEGF

Rising
+55%new papersScore 64
20212026

Faricimab and high-dose aflibercept for retinal disease.

428 papers / yr26 new trials
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Myopia control in children

Rising
+19%new papersScore 57
20212026

Atropine drops, defocus lenses and orthokeratology to slow myopia.

Key point: In myopic children, atropine efficacy increased nonlinearly with concentration and may plateau, while higher doses were associated with decreased accommodation and photophobia.

567 papers / yr79 new trials1 new guideline
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Ischaemic optic neuropathy

Steady
-1%new papersScore 52
20212026

Non-arteritic anterior ischaemic optic neuropathy, including reports linked to GLP-1 drugs.

Key point: In acute NAION, increased early optic nerve head swelling rates were associated with visual field and visual acuity worsening by month 6.

403 papers / yr7 new trials2 new guidelines
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AI in retinal imaging

Steady
+18%new papersScore 51
20212026

Deep learning on fundus photos and OCT, including signs of systemic disease.

1,425 papers / yr42 new trials2 new guidelines
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Diabetic retinopathy screening

Steady
+20%new papersScore 48
20212026

Screening for diabetic retinopathy, including autonomous AI.

522 papers / yr24 new trials1 new guideline
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Gene therapy for inherited retinal disease

Steady
+16%new papersScore 41
20212026

Gene therapy and optogenetics for inherited retinal dystrophies.

181 papers / yr6 new trials
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See all 12 ophthalmology topics

Every rising topic, with the papers behind it. Free for doctors.

How the Trend Score works

Four signals

Growth in new papers (35%), growth in randomised trials, meta-analyses and systematic reviews (25%), new clinical trials registered (20%), and new guidelines and consensus statements (20%), each over the last 12 months against the 12 before.

A score out of 100

Each signal is ranked against every topic we follow, so a score of 90 means the topic is ahead of about 90% of them. Rising fast: 80 and above. Rising: 55 to 79. Emerging: fewer than 100 papers the year before, too few to rank.

What it does not tell you

More research on a topic is not evidence that a treatment works. Open a topic to read the papers and guidelines themselves. Counts come from PubMed and ClinicalTrials.gov.