Myopia control in children
Atropine drops, defocus lenses and orthokeratology to slow myopia.
Key point
In myopic children, atropine efficacy increased nonlinearly with concentration and may plateau, while higher doses were associated with decreased accommodation and photophobia.
From: Efficacy, tolerability, and threshold effect of atropine eye drops for myopia control: A systematic review and dose-response meta-analysis (Surv Ophthalmol, 2026 Nov-Dec) ↗Papers per year
Each bar is 12 months; the last one ends 17 Oct 2026. New trials in the same years: 39, 47, 45, 47, 79.
New guidelines and consensus this year
All papers from the last 12 months
567 papers (18 Oct 2025 – 17 Oct 2026), newest first. Loading the full list…
- Effect of pH and Benzalkonium Chloride in Low-Dose Atropine on Pupil Dilation in Dutch Belted RabbitsJ Ocul Pharmacol Ther2026 NovPMID 42189004
- Efficacy, tolerability, and threshold effect of atropine eye drops for myopia control: A systematic review and dose-response meta-analysisSurv Ophthalmol2026 Nov-DecPMID 42070753Meta-analysisSystematic review
- Effects of high-intensity light on early lens-induced myopia in chicks: optical coherence tomography assessmentInt J Ophthalmol2026PMID 42761646
- Subtype-Specific Efficacy of Adrenoceptor Agonists in Inhibiting Lens-Induced Myopia in ChicksOphthalmic Physiol Opt2026 Oct 16PMID 42886331
- The Visual Impact of Uncorrected Astigmatism in Eyes Fitted with Dual Focus Myopia Control LensesOphthalmic Physiol Opt2026 Oct 15PMID 42878998
- [Adjustment of contact lens parameters to improve insufficient sagittal height for treatment of corneal injury: a case report]Zhonghua Yan Ke Za Zhi2026 Oct 11PMID 42855785
- Defocus Incorporated Multiple Segments (DIMS) spectacle lenses versus 0.01% atropine for myopia control: Two-year randomised trial in children from Central EuropeJ Optom2026 Oct 9PMID 42855355
- Real World Axial Elongation in Children Wearing Diversified Segmental Defocus Optimization Spectacle Lenses: A Longitudinal Cohort Study with External BenchmarksClin Optom (Auckl)2026PMID 42871117
- Effect of Low-Dose Atropine on Choroidal and Anterior Scleral Thickness in Myopic Egyptian Children: A Randomized Controlled TrialCurr Eye Res2026 Oct 8PMID 42850035
- Electroretinogram response changes in a guinea pig myopia model treated with different atropine concentrationsBiochem Biophys Res Commun2026 Oct 8PMID 42636766
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Key point: In acute NAION, increased early optic nerve head swelling rates were associated with visual field and visual acuity worsening by month 6.
AI in retinal imaging
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Minimally invasive glaucoma surgery
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Key point: Phaco-iStent and phaco-KDB both significantly reduced intraocular pressure and glaucoma medication burden with few postoperative complications.
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How these numbers are counted
PubMed query, searched in titles and abstracts by publication date:
myopia[tiab] AND (atropine[tiab] OR "myopia control"[tiab] OR orthokeratology[tiab] OR defocus[tiab])Trials: ClinicalTrials.gov studies first submitted in each 12-month window that match the same terms. A query can miss synonyms or catch unrelated papers, so treat counts as approximate.