Deprescribing
Planned reduction or stopping of medicines that may no longer benefit the patient.
Key point
Deprescribing statins is suggested for older adults at end of life; continuation is suggested for primary or secondary prevention otherwise.
From: Deprescribing statins for adults 65 years of age and older: Evidence-based clinical practice guideline (Can Fam Physician, 2026 Sep) ↗Papers per year
Each bar is 12 months; the last one ends 17 Oct 2026. New trials in the same years: 0, 0, 0, 0, 0.
New guidelines and consensus this year
- Commentary on: The American Society of Clinical Psychopharmacology task force consensus statement on the deprescribing of stimulant medications in adults with ADHDEur Neuropsychopharmacol2026 Nov
- The American Society of Clinical Psychopharmacology task force consensus statement on the deprescribing of stimulant medications in adults with ADHD(✰)Eur Neuropsychopharmacol2026 Oct
- A qualitative analysis to identify implementation strategies for a deprescribing clinical practice guideline using the CFIR-ERIC Matching Tool: perspectives from consumers and professional stakeholdersInt J Clin Pharm2026 Sep 3
- Deprescribing statins for adults 65 years of age and older: Evidence-based clinical practice guidelineCan Fam Physician2026 Sep
- Generative AI in the Care of Older Adults: A Position Statement From the American Geriatrics SocietyJ Am Geriatr Soc2026 Jul 21
All papers from the last 12 months
731 papers (18 Oct 2025 – 17 Oct 2026), newest first. Loading the full list…
- Risk factors for benzodiazepine deprescribing failure after discharge from an acute geriatric ward: A retrospective cohort studyArch Gerontol Geriatr2026 DecPMID 42785158
- Barriers and motivators for opioid deprescribing among Danish adults receiving long-term treatment with short-acting opioids: an exploratory qualitative study in primary care informed by self-determination theoryScand J Prim Health Care2026 DecPMID 42655883
- Medication safety in older adults in India: an integrative PhD synthesis of direct evidence and contextual implementation evidenceGlob Health Action2026 DecPMID 42605781Systematic review
- The prevalence and impact of medication-related harm in people living with dementia - a systematic review and meta-analysisRes Social Adm Pharm2026 DecPMID 42542413Meta-analysisSystematic review
- Pharmacological treatment of late-life major depressive disorder - Results from the AMSP drug surveillance program from 2007 to 2023J Affect Disord2026 Dec 1PMID 42503320
- Self-perceived learning outcomes of academic detailing discussing rational therapy with proton pump inhibitors among general practitioners in NorwayScand J Prim Health Care2026 DecPMID 42307464
- Deprescribing in dermatologyJ Dermatolog Treat2026 DecPMID 41958435
- Patients' perspectives on deprescribing in swedish primary care: an exploratory survey studyScand J Prim Health Care2026 DecPMID 41766353
- Association Between Trust in Healthcare Providers and Readiness to Deprescribe in Older Adults: A Cross-Sectional Comparative Study in the United States and JapanJ Gen Fam Med2026 NovPMID 42846814
- Identifying Medication Discontinuations Using Text Searching and Clinical DataMed Care2026 Nov 1PMID 42593400
More internal medicine trends
All specialties →GLP-1 drugs for obesity
GLP-1 based medicines such as semaglutide and tirzepatide for weight management.
Polypharmacy
Use of many medicines at once and its risks.
Frailty assessment
Tools and scores to identify frailty in older adults.
Hospital at home
Acute hospital-level care delivered in the patient's home.
Key point: Home hospitalization presents an effective strategy for comprehensive heart failure management, reducing hospital-related complications and promoting patient-centered care.
Remote patient monitoring
Tracking patients' vital signs and symptoms at home with connected devices.
Key point: Remote monitoring is a standard tool for managing patients with cardiac implantable electronic devices, offering early event detection, fewer routine visits, and reduced mortality.
Hyponatremia
Low blood sodium, its causes and correction.
Key point: Hyponatremia in cirrhosis should be worked up with dietary and medication history, electrolyte/kidney review, bleeding and infection assessment, and thyroid/adrenal evaluation.
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How these numbers are counted
PubMed query, searched in titles and abstracts by publication date:
deprescrib*[tiab]Trials: ClinicalTrials.gov studies first submitted in each 12-month window that match the same terms. A query can miss synonyms or catch unrelated papers, so treat counts as approximate.