Hyponatremia
Low blood sodium, its causes and correction.
Key point
Hyponatremia in cirrhosis should be worked up with dietary and medication history, electrolyte/kidney review, bleeding and infection assessment, and thyroid/adrenal evaluation.
From: AGA Clinical Practice Update on the Management of Ascites, Volume Overload, and Hyponatremia in Cirrhosis: Expert Review (Gastroenterology, 2025 Dec) ↗Papers per year
Each bar is 12 months; the last one ends 17 Oct 2026. New trials in the same years: 24, 23, 30, 19, 24.
New guidelines and consensus this year
All papers from the last 12 months
1,025 papers (18 Oct 2025 – 17 Oct 2026), newest first. Loading the full list…
- Deciphering aldosterone deficiency and pseudodeficiency in infancy by targeted GC-MS urinary steroid metabotypingJ Steroid Biochem Mol Biol2027 JanPMID 42603653
- Does hydrochlorothiazide-associated hyponatremia in hypertensive individuals have a genetic origin?Clin Exp Hypertens2026 Dec 31PMID 42454948
- Prevalence and impact of hyponatremia in chronic obstructive pulmonary disease. A systematic review and meta-analysisLibyan J Med2026 Dec 31PMID 41846300Meta-analysisSystematic review
- Biochemical characteristics associated with spironolactone use in hospitalized patients with hypotonic hyponatraemiaAnn Med2026 DecPMID 42752325
- Chronic hyponatraemia with a reset osmostat: when abnormal is normalPediatr Nephrol2026 DecPMID 42377490
- Prognostic factors in malaria patients with acute kidney injury: a systematic review and meta analysisRen Fail2026 DecPMID 42185742Meta-analysisSystematic review
- Multiple electrolyte imbalances in hospitalized patients: a multimorbidity perspective from a large, retrospective cohort studyAnn Med2026 DecPMID 41649147
- Predictions of cisplatin-induced hyponatremia in patients with malignancy: a retrospective cohort survey of all cisplatin administration in clinical practiceClin Exp Nephrol2026 NovPMID 42496909
- Association between kidney function and risk of hyponatremia: a single-center, cross-sectional study in the outpatient settingClin Exp Nephrol2026 NovPMID 42347885
- Epidemiology of early onset hyponatremia in extremely preterm neonates: A retrospective observational studyJ Neonatal Perinatal Med2026 NovPMID 42017768
More internal medicine trends
All specialties →Deprescribing
Planned reduction or stopping of medicines that may no longer benefit the patient.
Key point: Deprescribing statins is suggested for older adults at end of life; continuation is suggested for primary or secondary prevention otherwise.
Hospital at home
Acute hospital-level care delivered in the patient's home.
Key point: Home hospitalization presents an effective strategy for comprehensive heart failure management, reducing hospital-related complications and promoting patient-centered care.
Remote patient monitoring
Tracking patients' vital signs and symptoms at home with connected devices.
Key point: Remote monitoring is a standard tool for managing patients with cardiac implantable electronic devices, offering early event detection, fewer routine visits, and reduced mortality.
Social determinants of health
Social and economic conditions that shape health outcomes.
Intravenous iron
Intravenous iron formulations for iron deficiency.
Key point: In chronic kidney disease, transferrin saturation and ferritin thresholds guide iron therapy, with intravenous iron preferred over oral iron in people receiving hemodialysis.
Long COVID
Symptoms persisting or appearing after acute SARS-CoV-2 infection.
Key point: Evidence-based recommendations suggest vaccination or antivirals during acute COVID-19 to prevent long COVID, but certainty is very low to moderate.
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How these numbers are counted
PubMed query, searched in titles and abstracts by publication date:
hyponatremia[tiab] OR hyponatraemia[tiab]Trials: ClinicalTrials.gov studies first submitted in each 12-month window that match the same terms. A query can miss synonyms or catch unrelated papers, so treat counts as approximate.