High-sensitivity troponin pathways
Rapid rule-in and rule-out algorithms for myocardial infarction using high-sensitivity troponin.
Key point
The ESC 0/1-hour pathway did not increase 4-hour discharge versus 0/3-hour testing but was noninferior for discharge safety.
From: Accelerated Diagnostic Pathways for Suspected Acute Coronary Syndrome in Practice: A Randomized Trial of 0/1-Hour vs 0/3-Hour Troponin Testing (J Am Coll Cardiol, 2026 Sep 15) ↗Papers per year
Each bar is 12 months; the last one ends 17 Oct 2026. New trials in the same years: 5, 13, 8, 7, 14.
New guidelines and consensus this year
All papers from the last 12 months
136 papers (18 Oct 2025 – 17 Oct 2026), newest first. Loading the full list…
- Rule-Out yield of the European society of cardiology 0/1-Hour troponin protocol in frail and non-frail octogenariansIr J Med Sci2026 Oct 15PMID 42879120
- A 0/2-Hour Algorithm Using a Novel Point-of-Care High-Sensitivity Cardiac Troponin I Assay for Suspected Myocardial InfarctionAm Heart J2026 Oct 13PMID 42869272
- Complications associated with thoracic endovascular aortic repair: highlighting the role of peri- and post-operative cardiac monitoringExpert Rev Cardiovasc Ther2026 Oct 12PMID 42859403Review
- Self-inflicted thoracoabdominal nail-gun injury presenting as STEMI: diagnostic challenges in a time-critical care pathwayJ Surg Case Rep2026 OctPMID 42859707
- Functional, Hemodynamic and Molecular Determinants for Evaluating the Efficacy of Sodium-glucose Cotransporter-2 Inhibitor Therapy in Diabetic Kidney DiseaseAnn Afr Med2026 Oct 7PMID 42844933
- Beyond troponin: emerging biomarker strategies to differentiate type 1 from type 2 myocardial infarctionCurr Probl Cardiol2026 OctPMID 42362128Review
- Clinical performance of the next generation Elecsys Troponin T high-sensitivity Gen 6 assay in acute coronary syndrome (PERFORM-TSIX): study designClin Res Cardiol2026 OctPMID 41553478
- Impact of subthreshold troponin levels and temporal trends on short term adverse cardiovascular outcomes in patients discharged from the emergency department: a RACE-IT trial substudyClin Res Cardiol2026 OctPMID 41284048RCT
- Differential effects of a 0/1-hour high-sensitivity troponin algorithm across academic and community emergency departmentsAm J Emerg Med2026 Sep 18PMID 42784939
- Accelerated Diagnostic Pathways for Suspected Acute Coronary Syndrome in Practice: A Randomized Trial of 0/1-Hour vs 0/3-Hour Troponin TestingJ Am Coll Cardiol2026 Sep 15PMID 42159533RCT
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How these numbers are counted
PubMed query, searched in titles and abstracts by publication date:
("high-sensitivity troponin"[tiab] OR "high-sensitivity cardiac troponin"[tiab]) AND (pathway*[tiab] OR algorithm*[tiab] OR "rule-out"[tiab])Trials: ClinicalTrials.gov studies first submitted in each 12-month window that match the same terms. A query can miss synonyms or catch unrelated papers, so treat counts as approximate.