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All emergency medicine trends
SteadyEmergency medicine · updated 18 Oct 2026

Whole blood in trauma resuscitation

Transfusing whole blood instead of separate components in bleeding trauma patients.

54PubDaily Trend Score
+16%new papers vs last year
1567new trials registered
5new guidelines this year

Papers per year

Each bar is 12 months; the last one ends 17 Oct 2026. New trials in the same years: 939, 1035, 1162, 1312, 1567.

New guidelines and consensus this year

  1. Post-Transfusion Management of RhD-Negative Females of Childbearing Potential Who Receive RhD-Positive Low-Titer Group O Whole Blood and Red Blood Cells During Trauma Resuscitation: A Joint Position Statement and Resource Document of the American College of Surgeons Committee on Trauma (ACS-COT), Prehospital Blood Transfusion Coalition (PBTC), National Association of Emergency Medical Services Physicians (NAEMSP), Trauma Hemostasis and Oxygenation Research (THOR) Network, and Allo Hope Foundation (AHF)
    J Am Coll Surg2026 Jul 22
  2. Alternative models of consent in out-of-hospital transfusion trials: a CAN-PATT position statement supporting exception from prospective consent with opt-out notification
    Scand J Trauma Resusc Emerg Med2026 Jun 9
  3. Emergent Transfusion and Hemolytic Disease of the Fetus and Newborn Risk Mitigation in Females of Childbearing Potential with Life-Threatening Bleeding: A Clinical Practice Guideline
    J Am Coll Surg2026 May 1
  4. Do not forget the cryoprecipitate: The impact of the 2019 Joint Trauma System Damage Control Resuscitation Clinical Practice Guideline on mortality
    J Trauma Acute Care Surg2026 Feb 1
  5. A Clinical Practice Guideline for the Management of Pregnancy Alloimmunized to Red Blood Cell Antigens
    JAMA Netw Open2025 Nov 3

All papers from the last 12 months

288 papers (18 Oct 2025 – 17 Oct 2026), newest first. Loading the full list…

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  1. Hierarchically sized chitosan hemostatic particles with electrostatic-hydrophobic synergy for rapid and effective control of arterial hemorrhage
    Colloids Surf B Biointerfaces2026 DecPMID 42659844
  2. Comparative efficacy of fluid resuscitation strategies in a rat model of traumatic cardiac arrest
    Resusc Plus2026 NovPMID 42774566
  3. Ziyuglycoside I attenuates coagulopathy induced by Deinagkistrodon acutus venom in human whole blood: a thromboelastography-based study
    Toxicon2026 Nov 1PMID 42595058
  4. Efficacy and safety of prehospital whole blood resuscitation in traumatic haemorrhagic shock a systematic review and meta-analysis
    Am J Emerg Med2026 NovPMID 42526297Meta-analysisSystematic review
  5. Paradoxical viper envenomation: minimal local manifestations with fatal intracranial hemorrhage- an autopsy case report
    Leg Med (Tokyo)2026 Oct 12PMID 42868940
  6. Acute hemorrhagic shock from vaginal laceration during intercourse requiring operative management
    Am J Emerg Med2026 Oct 11PMID 42874252
  7. Mortality Risk Across Early RBC-Equivalent Transfusion Burden in the Whole Blood Era
    J Am Coll Surg2026 Oct 8PMID 42847426
  8. Aberrant erythrocyte rigidity in JAK2(V617F) myeloproliferative neoplasms underlies concurrent thrombosis and hemorrhage
    Sci Transl Med2026 Oct 7PMID 42842724
  9. Rethinking Platelet Dysfunction in Traumatic Brain Injury: From Platelet Count to Hemostatic Phenotype
    Neurocrit Care2026 Oct 6PMID 42839199
  10. Enhancing Far-Forward Resuscitation: A Quantitative Laboratory Analysis of Blood Warmer Devices Used in Austere Environments
    Prehosp Emerg Care2026 Oct 6PMID 42766494

More emergency medicine trends

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Point-of-care ultrasound in the ED

Rising
+21%new papersScore 78
20212026

Bedside ultrasound performed by emergency clinicians for diagnosis and procedures.

Key point: Focused transesophageal echocardiography should only be performed during advanced cardiopulmonary resuscitation or unclear shock when focused transthoracic echocardiography cannot clarify the issue.

532 papers / yr46 new trials5 new guidelines
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High-sensitivity troponin pathways

Rising
+21%new papersScore 59
20212026

Rapid rule-in and rule-out algorithms for myocardial infarction using high-sensitivity troponin.

Key point: The ESC 0/1-hour pathway did not increase 4-hour discharge versus 0/3-hour testing but was noninferior for discharge safety.

136 papers / yr14 new trials1 new guideline
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ED boarding and crowding

Rising
+30%new papersScore 59
20212026

Patients held in the emergency department while waiting for an inpatient bed, and its effects.

421 papers / yr13 new trials2 new guidelines
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Tranexamic acid in bleeding

Steady
+19%new papersScore 46
20212026

Tranexamic acid in trauma and other acute haemorrhage.

Key point: Tranexamic acid does not affect all-cause mortality, functional outcomes, neurological impairment, or hematoma expansion in spontaneous intracerebral hemorrhage, despite reducing hematoma volume.

386 papers / yr37 new trials1 new guideline
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Video laryngoscopy

Steady
+17%new papersScore 38
20212026

Video laryngoscopes for tracheal intubation.

Key point: For neonatal and infant airway management, videolaryngoscopy is the first choice for intubation, with apneic oxygenation during the attempt.

432 papers / yr0 new trials5 new guidelines
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Extracorporeal CPR (ECPR)

Steady
+17%new papersScore 37
20212026

Using ECMO during cardiac arrest when conventional CPR fails.

Key point: Extracorporeal CPR may be considered for selected in-hospital pediatric arrests unresponsive to conventional CPR in appropriately resourced hospitals, with insufficient evidence for out-of-hospital use.

376 papers / yr7 new trials3 new guidelines
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How these numbers are counted

PubMed query, searched in titles and abstracts by publication date:

"whole blood"[tiab] AND (trauma*[tiab] OR hemorrhag*[tiab] OR haemorrhag*[tiab])

Trials: ClinicalTrials.gov studies first submitted in each 12-month window that match the same terms. A query can miss synonyms or catch unrelated papers, so treat counts as approximate.