Whole blood in trauma resuscitation
Transfusing whole blood instead of separate components in bleeding trauma patients.
Papers per year
Each bar is 12 months; the last one ends 17 Oct 2026. New trials in the same years: 939, 1035, 1162, 1312, 1567.
New guidelines and consensus this year
- Post-Transfusion Management of RhD-Negative Females of Childbearing Potential Who Receive RhD-Positive Low-Titer Group O Whole Blood and Red Blood Cells During Trauma Resuscitation: A Joint Position Statement and Resource Document of the American College of Surgeons Committee on Trauma (ACS-COT), Prehospital Blood Transfusion Coalition (PBTC), National Association of Emergency Medical Services Physicians (NAEMSP), Trauma Hemostasis and Oxygenation Research (THOR) Network, and Allo Hope Foundation (AHF)J Am Coll Surg2026 Jul 22
- Alternative models of consent in out-of-hospital transfusion trials: a CAN-PATT position statement supporting exception from prospective consent with opt-out notificationScand J Trauma Resusc Emerg Med2026 Jun 9
- Emergent Transfusion and Hemolytic Disease of the Fetus and Newborn Risk Mitigation in Females of Childbearing Potential with Life-Threatening Bleeding: A Clinical Practice GuidelineJ Am Coll Surg2026 May 1
- Do not forget the cryoprecipitate: The impact of the 2019 Joint Trauma System Damage Control Resuscitation Clinical Practice Guideline on mortalityJ Trauma Acute Care Surg2026 Feb 1
- A Clinical Practice Guideline for the Management of Pregnancy Alloimmunized to Red Blood Cell AntigensJAMA Netw Open2025 Nov 3
All papers from the last 12 months
288 papers (18 Oct 2025 – 17 Oct 2026), newest first. Loading the full list…
- Hierarchically sized chitosan hemostatic particles with electrostatic-hydrophobic synergy for rapid and effective control of arterial hemorrhageColloids Surf B Biointerfaces2026 DecPMID 42659844
- Comparative efficacy of fluid resuscitation strategies in a rat model of traumatic cardiac arrestResusc Plus2026 NovPMID 42774566
- Ziyuglycoside I attenuates coagulopathy induced by Deinagkistrodon acutus venom in human whole blood: a thromboelastography-based studyToxicon2026 Nov 1PMID 42595058
- Efficacy and safety of prehospital whole blood resuscitation in traumatic haemorrhagic shock a systematic review and meta-analysisAm J Emerg Med2026 NovPMID 42526297Meta-analysisSystematic review
- Paradoxical viper envenomation: minimal local manifestations with fatal intracranial hemorrhage- an autopsy case reportLeg Med (Tokyo)2026 Oct 12PMID 42868940
- Acute hemorrhagic shock from vaginal laceration during intercourse requiring operative managementAm J Emerg Med2026 Oct 11PMID 42874252
- Mortality Risk Across Early RBC-Equivalent Transfusion Burden in the Whole Blood EraJ Am Coll Surg2026 Oct 8PMID 42847426
- Aberrant erythrocyte rigidity in JAK2(V617F) myeloproliferative neoplasms underlies concurrent thrombosis and hemorrhageSci Transl Med2026 Oct 7PMID 42842724
- Rethinking Platelet Dysfunction in Traumatic Brain Injury: From Platelet Count to Hemostatic PhenotypeNeurocrit Care2026 Oct 6PMID 42839199
- Enhancing Far-Forward Resuscitation: A Quantitative Laboratory Analysis of Blood Warmer Devices Used in Austere EnvironmentsPrehosp Emerg Care2026 Oct 6PMID 42766494
More emergency medicine trends
All specialties →Point-of-care ultrasound in the ED
Bedside ultrasound performed by emergency clinicians for diagnosis and procedures.
Key point: Focused transesophageal echocardiography should only be performed during advanced cardiopulmonary resuscitation or unclear shock when focused transthoracic echocardiography cannot clarify the issue.
High-sensitivity troponin pathways
Rapid rule-in and rule-out algorithms for myocardial infarction using high-sensitivity troponin.
Key point: The ESC 0/1-hour pathway did not increase 4-hour discharge versus 0/3-hour testing but was noninferior for discharge safety.
ED boarding and crowding
Patients held in the emergency department while waiting for an inpatient bed, and its effects.
Tranexamic acid in bleeding
Tranexamic acid in trauma and other acute haemorrhage.
Key point: Tranexamic acid does not affect all-cause mortality, functional outcomes, neurological impairment, or hematoma expansion in spontaneous intracerebral hemorrhage, despite reducing hematoma volume.
Video laryngoscopy
Video laryngoscopes for tracheal intubation.
Key point: For neonatal and infant airway management, videolaryngoscopy is the first choice for intubation, with apneic oxygenation during the attempt.
Extracorporeal CPR (ECPR)
Using ECMO during cardiac arrest when conventional CPR fails.
Key point: Extracorporeal CPR may be considered for selected in-hospital pediatric arrests unresponsive to conventional CPR in appropriately resourced hospitals, with insufficient evidence for out-of-hospital use.
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How these numbers are counted
PubMed query, searched in titles and abstracts by publication date:
"whole blood"[tiab] AND (trauma*[tiab] OR hemorrhag*[tiab] OR haemorrhag*[tiab])Trials: ClinicalTrials.gov studies first submitted in each 12-month window that match the same terms. A query can miss synonyms or catch unrelated papers, so treat counts as approximate.