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All anesthesiology trends
RisingAnesthesiology · updated 18 Oct 2026

Liposomal bupivacaine

Studies of liposomal bupivacaine for postoperative analgesia and regional blocks.

66PubDaily Trend Score
+40%new papers vs last year
40new trials registered
0new guidelines this year

Papers per year

Each bar is 12 months; the last one ends 17 Oct 2026. New trials in the same years: 21, 17, 37, 28, 40.

All papers from the last 12 months

202 papers (18 Oct 2025 – 17 Oct 2026), newest first. Loading the full list…

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  1. Liposomal bupivacaine versus ropivacaine for surgical site infiltration in lumbar fusion: a prospective randomized controlled trial
    Ann Med2026 DecPMID 42504098RCT
  2. Thoracic paravertebral block with different doses of liposomal bupivacaine versus ropivacaine for postoperative analgesia in single-port thoracoscopic lung surgery: a randomized clinical trial
    Ann Med2026 DecPMID 42342240RCT
  3. Effect of different liposomal bupivacaine concentrations in ultrasound-guided superior trunk block on postoperative analgesia and mobility: a randomized double-blind controlled trial protocol for shoulder arthroscopy
    Ann Med2026 DecPMID 42338183RCT
  4. Comparison of liposomal bupivacaine and bupivacaine hydrochloride intercostal nerve blocks for postoperative analgesia after thoracic surgery: a multicenter, randomized, three arms trial protocol
    Ann Med2026 DecPMID 41560407
  5. Exparel vs. Marcaine for donor site analgesia in atraumatic lower extremity wound STSG: Does neuropathy alter the pain equation?
    J Plast Reconstr Aesthet Surg2026 NovPMID 42580963
  6. A Quality Initiative for Posterior Spinal Fusion in Adolescent Idiopathic Scoliosis (AIS): Liposomal Bupivacaine With Dexamethasone Use Results in Substantial Reduction in Inpatient Opioid Use
    J Pediatr Orthop2026 Nov-Dec 01PMID 42438187
  7. Efficacy of Liposomal Bupivacaine for Pain Control in Pediatric Patients With Adolescent Idiopathic Scoliosis Undergoing Instrumented Posterior Spinal Fusion
    Spine (Phila Pa 1976)2026 Nov 1PMID 41150701
  8. Liposomal bupivacaine does not prolong neuraxial blockade and produces less consistent motor blockade than bupivacaine hydrochloride in inland bearded dragons (Pogona vitticeps)
    Am J Vet Res2026 Oct 15PMID 42880342
  9. Ilioinguinal-Transversus Abdominis Plane (I-TAP) Block with Liposomal Bupivacaine for Analgesia After Cesarean Delivery: A Randomized Controlled Trial
    Drug Des Devel Ther2026PMID 42871156RCT
  10. Liposomal Bupivacaine Combined with Bupivacaine vs Ropivacaine for Paravertebral Blockade in Single-Port Video-Assisted Thoracoscopic Surgery: A Propensity-Matched Comparison of Postoperative Opioid Use
    Drug Des Devel Ther2026PMID 42866140

More anesthesiology trends

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Opioid-free anaesthesia

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+77%new papersScore 78
20212026

Anaesthesia techniques that avoid or minimise intraoperative opioids.

722 papers / yr121 new trials
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GLP-1 drugs and perioperative aspiration

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+60%new papersScore 75
20212026

Delayed gastric emptying with GLP-1 based medicines and the risk at anaesthesia.

Key point: GLP-1 RA-based therapies should continue in most patients, with individualized risk assessment and gastric ultrasound when delayed gastric emptying is suspected.

376 papers / yr34 new trials3 new guidelines
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Intraoperative hypotension

Rising
+45%new papersScore 63
20212026

Low blood pressure during surgery and its effects on outcomes.

Key point: In adults undergoing elective noncardiac surgery, targeting higher intraoperative blood pressure values does not improve major postoperative outcomes compared with routine management.

343 papers / yr79 new trials
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Postoperative delirium

Rising
+29%new papersScore 60
20212026

Acute confusion after surgery, its prevention and outcomes.

1,008 papers / yr173 new trials
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Fascial plane blocks

Steady
+13%new papersScore 48
20212026

Regional blocks such as the erector spinae plane and quadratus lumborum blocks.

Key point: For adults, fascial plane blocks are strongly recommended to reduce pain and/or opioid requirements after open cardiothoracic, abdominal, retroperitoneal, pelvic surgeries and mastectomy.

678 papers / yr270 new trials1 new guideline
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EEG-guided anaesthesia

Steady
+23%new papersScore 48
20212026

Processed EEG monitoring to guide anaesthetic depth.

337 papers / yr114 new trials
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How these numbers are counted

PubMed query, searched in titles and abstracts by publication date:

"liposomal bupivacaine"[tiab] OR "liposome bupivacaine"[tiab]

Trials: ClinicalTrials.gov studies first submitted in each 12-month window that match the same terms. A query can miss synonyms or catch unrelated papers, so treat counts as approximate.