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Research trends

What anesthesiology is researching now

The topics gaining the most ground, ranked by the PubDaily Trend Score: new research, stronger evidence, new trials and new guidelines. 291 topics in 22 specialties, updated 18 Oct 2026.

Monthly reportThe fastest-rising topics in medicine: October 2026Read →
14 topics · anesthesiology

Opioid-free anaesthesia

Rising
+77%new papersScore 78
20212026

Anaesthesia techniques that avoid or minimise intraoperative opioids.

722 papers / yr121 new trials
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GLP-1 drugs and perioperative aspiration

Rising
+60%new papersScore 75
20212026

Delayed gastric emptying with GLP-1 based medicines and the risk at anaesthesia.

Key point: GLP-1 RA-based therapies should continue in most patients, with individualized risk assessment and gastric ultrasound when delayed gastric emptying is suspected.

376 papers / yr34 new trials3 new guidelines
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Liposomal bupivacaine

Rising
+40%new papersScore 66
20212026

Studies of liposomal bupivacaine for postoperative analgesia and regional blocks.

202 papers / yr40 new trials
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Intraoperative hypotension

Rising
+45%new papersScore 63
20212026

Low blood pressure during surgery and its effects on outcomes.

Key point: In adults undergoing elective noncardiac surgery, targeting higher intraoperative blood pressure values does not improve major postoperative outcomes compared with routine management.

343 papers / yr79 new trials
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Postoperative delirium

Rising
+29%new papersScore 60
20212026

Acute confusion after surgery, its prevention and outcomes.

1,008 papers / yr173 new trials
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Fascial plane blocks

Steady
+13%new papersScore 48
20212026

Regional blocks such as the erector spinae plane and quadratus lumborum blocks.

Key point: For adults, fascial plane blocks are strongly recommended to reduce pain and/or opioid requirements after open cardiothoracic, abdominal, retroperitoneal, pelvic surgeries and mastectomy.

678 papers / yr270 new trials1 new guideline
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See all 14 anesthesiology topics

Every rising topic, with the papers behind it. Free for doctors.

How the Trend Score works

Four signals

Growth in new papers (35%), growth in randomised trials, meta-analyses and systematic reviews (25%), new clinical trials registered (20%), and new guidelines and consensus statements (20%), each over the last 12 months against the 12 before.

A score out of 100

Each signal is ranked against every topic we follow, so a score of 90 means the topic is ahead of about 90% of them. Rising fast: 80 and above. Rising: 55 to 79. Emerging: fewer than 100 papers the year before, too few to rank.

What it does not tell you

More research on a topic is not evidence that a treatment works. Open a topic to read the papers and guidelines themselves. Counts come from PubMed and ClinicalTrials.gov.