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All internal medicine trends
Rising fastInternal medicine · updated 18 Oct 2026

Cardiovascular-kidney-metabolic syndrome

The linked burden of cardiovascular disease, kidney disease, diabetes and obesity.

98PubDaily Trend Score
+153%new papers vs last year
21new trials registered
8new guidelines this year

Papers per year

Each bar is 12 months; the last one ends 17 Oct 2026. New trials in the same years: 0, 0, 3, 9, 21.

New guidelines and consensus this year

  1. Pharmacological treatment strategies to prevent heart failure across the cardiovascular-kidney-metabolic spectrum: an EJHF Expert Consensus Statement
    Eur J Heart Fail2026 Oct 1
  2. Executive Summary of the ASN Kidney Health Guidance on the Cardiovascular‑Kidney‑Metabolic Syndrome
    J Am Soc Nephrol2026 Oct 1
  3. ASN Kidney Health Guidance on the Cardiovascular-Kidney-Metabolic Syndrome
    J Am Soc Nephrol2026 Oct 1
  4. Cardiovascular-kidney-metabolic syndrome: definition, staging, diagnosis and therapeutic management. An expert consensus statement of the Committee of cardiovascular-kidney-metabolic syndrome of the Hellenic Society of Cardiology
    Hellenic J Cardiol2026 Sep 4
  5. Assessment and management of cardiovascular-kidney-liver metabolic-syndrome in the primary care setting: A multidisciplinary consensus statement
    Eur J Intern Med2026 Aug

All papers from the last 12 months

1,111 papers (18 Oct 2025 – 17 Oct 2026), newest first. Loading the full list…

Open this search in PubMed
  1. Cardiovascular-Kidney-Metabolic syndrome and suicidal death in a nationwide cohort study
    J Affect Disord2027 Jan 1PMID 42822542
  2. Cardiovascular-kidney-metabolic syndrome through the lens of gut‑derived uremic toxins
    Gut Microbes2026 Dec 31PMID 42296178Review
  3. SPISE index and ensemble machine learning refine cardiovascular risk stratification in stage 0-3 CKM syndrome
    Aging Male2026 Dec 31PMID 42101474
  4. Cardiometabolic index and advanced cardiovascular-kidney-metabolic syndrome in two population-based cohorts from the USA and China
    Clin Exp Hypertens2026 Dec 31PMID 41914048
  5. Amylin and the renin-angiotensin system: risk or opportunity in amylin-based therapy?
    Lancet2026 Dec 20PMID 41207308Review
  6. Biological age acceleration and cardiovascular-kidney-metabolic syndrome progression: evidence from UK Biobank and NHANES
    Ren Fail2026 DecPMID 42860781
  7. Metabolic syndrome score and cardiovascular disease risk in adults with cardiovascular-kidney-metabolic syndrome stages 0-3: A prospective cohort study
    Metabol Open2026 DecPMID 42840839
  8. Cardiovascular-Kidney-Metabolic Syndrome and Health Risk Behaviors in U.S. Adults
    AJPM Focus2026 DecPMID 42831201
  9. Cumulative non-HDL cholesterol exposure and risk of cardiovascular-kidney-metabolic syndrome progression: a nationwide longitudinal study from CHARLS
    J Diabetes Metab Disord2026 DecPMID 42798513
  10. Weight-adjusted waist index and risk of cardiovascular and all-cause mortality in chronic kidney disease: NHANES 2005-2018 analysis of 5,381 adults
    Ren Fail2026 DecPMID 42655969

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How these numbers are counted

PubMed query, searched in titles and abstracts by publication date:

"cardiovascular-kidney-metabolic"[tiab] OR "cardio-kidney-metabolic"[tiab]

Trials: ClinicalTrials.gov studies first submitted in each 12-month window that match the same terms. A query can miss synonyms or catch unrelated papers, so treat counts as approximate.