Large language models in clinical care
Chatbots and large language models used for clinical questions, documentation and patient communication.
Papers per year
Each bar is 12 months; the last one ends 17 Oct 2026. New trials in the same years: 2, 6, 40, 92, 183.
New guidelines and consensus this year
- Artificial intelligence in metabolic and bariatric surgery: current applications and future direction from the ASMBS Emerging Technology and Procedures CommitteeSurg Obes Relat Dis2026 Sep 29
- Improvement of Clinical Practice Guideline Appraisal by Human Experts and AI Agents by Using Structured Guidance: Systematic Review, Meta-Analysis, and Validation StudyJ Med Internet Res2026 Aug 26
- Evaluation of GPT-5, a Large Language Model, in Replicating German Clinical Practice Guideline Recommendations in Oral Oncology: A Cross-Sectional Concordance StudyJ Oral Pathol Med2026 Aug
- Generative AI in the Care of Older Adults: A Position Statement From the American Geriatrics SocietyJ Am Geriatr Soc2026 Jul 21
- Performance of Google NotebookLM for AI-assisted data extraction and consensus statement generation in a heterogenous systematic review on inflammatory bowel disease, obesity, and cardiometabolic comorbidities: A Methodological ReportmedRxiv2026 Jun 26
All papers from the last 12 months
7,079 papers (18 Oct 2025 – 17 Oct 2026), newest first. Loading the full list…
- Artificial Intelligence in suicide prevention: promise, peril, and clinical implications for clinical practiceDialogues Clin Neurosci2027 DecPMID 42862709Review
- Evaluation of Large Language Models in the Clinical Management of Patients With Upper Gastrointestinal Bleeding: Insights From Real-World Patient DataDEN Open2027 AprPMID 42428234
- AI-assisted post-mortem classification of vehicle trauma in free-roaming cats using transformer-based large language modelsVet Q2026 Dec 31PMID 42544936
- Autonomous radiotherapy planning via agentic orchestration using a multimodal TPS-integrated compound AI platformMach Learn Health2026 Dec 31PMID 42466075
- AI-assisted learning: ChatGPT for anamnesis in women's health educationMed Educ Online2026 Dec 31PMID 41932848
- Integrating ChatGPT into knowledge-retrieval tutorials in undergraduate medical education: a prospective evaluation of higher-order learning and feasibilityMed Educ Online2026 Dec 31PMID 41769797
- LLM-supported self-diagnosis and self-treatment of familial Mediterranean fever: a case reportEULAR Rheumatol Open2026 DecPMID 42857616
- Combating antimicrobial resistance through multimodal data via artificial intelligenceOne Health2026 DecPMID 42827724Review
- Online health information-seeking behavior during the preoperative period among patients with pancreatic tumors and caregivers in China: A qualitative studyAsia Pac J Oncol Nurs2026 DecPMID 42827600
- Proficiency of artificial intelligence in addressing patient frequently asked questions on oral lichen planusOral Surg Oral Med Oral Pathol Oral Radiol2026 DecPMID 42823233
More internal medicine trends
All specialties →Cardiovascular-kidney-metabolic syndrome
The linked burden of cardiovascular disease, kidney disease, diabetes and obesity.
GLP-1 drugs for obesity
GLP-1 based medicines such as semaglutide and tirzepatide for weight management.
Polypharmacy
Use of many medicines at once and its risks.
Frailty assessment
Tools and scores to identify frailty in older adults.
Deprescribing
Planned reduction or stopping of medicines that may no longer benefit the patient.
Key point: Deprescribing statins is suggested for older adults at end of life; continuation is suggested for primary or secondary prevention otherwise.
Hospital at home
Acute hospital-level care delivered in the patient's home.
Key point: Home hospitalization presents an effective strategy for comprehensive heart failure management, reducing hospital-related complications and promoting patient-centered care.
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How these numbers are counted
PubMed query, searched in titles and abstracts by publication date:
("large language model*"[tiab] OR ChatGPT[tiab] OR GPT-4[tiab]) AND (clinical[tiab] OR medicine[tiab] OR patient*[tiab])Trials: ClinicalTrials.gov studies first submitted in each 12-month window that match the same terms. A query can miss synonyms or catch unrelated papers, so treat counts as approximate.