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All internal medicine trends
SteadyInternal medicine · updated 18 Oct 2026

Intravenous iron

Intravenous iron formulations for iron deficiency.

Key point

In chronic kidney disease, transferrin saturation and ferritin thresholds guide iron therapy, with intravenous iron preferred over oral iron in people receiving hemodialysis.

From: Evaluation and Management of Anemia in Chronic Kidney Disease: Synopsis of the Kidney Disease: Improving Global Outcomes 2026 Clinical Practice Guideline (Ann Intern Med, 2026 Sep 15) ↗
39PubDaily Trend Score
+10%new papers vs last year
30new trials registered
6new guidelines this year

Papers per year

Each bar is 12 months; the last one ends 17 Oct 2026. New trials in the same years: 32, 36, 20, 29, 30.

New guidelines and consensus this year

  1. Evaluation and Management of Anemia in Chronic Kidney Disease: Synopsis of the Kidney Disease: Improving Global Outcomes 2026 Clinical Practice Guideline
    Ann Intern Med2026 Sep 15
  2. An Updated Algorithm for the Management of Restless Legs Syndrome
    Mayo Clin Proc2026 Sep
  3. No. 469 Iron Deficiency and Iron Deficiency Anemia in Obstetrics and Gynaecology
    J Obstet Gynaecol Can2026 Aug
  4. Position statement of the SEN Anemia Working Group: A critical and contextualized adaptation of the KDIGO 2026 anemia guidelines to the Spanish setting
    Nefrologia (Engl Ed)2026 Aug-Sep
  5. KDIGO 2026 Clinical Practice Guideline for Anemia in Chronic Kidney Disease (CKD): a commentary from the European Renal Best Practice (ERBP)
    Nephrol Dial Transplant2026 Jul 31

All papers from the last 12 months

370 papers (18 Oct 2025 – 17 Oct 2026), newest first. Loading the full list…

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  1. Risk of bone fracture following saccharated ferric oxide in Japan
    Bone2026 DecPMID 42628613
  2. Proactive iron supplementation alone in patients on chronic hemodialysis is not sufficient
    Ren Fail2026 DecPMID 42552952
  3. Expert consensus on the screening, diagnosis, and management of perinatal iron deficiency anemia in Egypt
    J Matern Fetal Neonatal Med2026 DecPMID 42476909
  4. Casemix-based budget impact analysis of ferric derisomaltose versus ferric carboxymaltose in patients with inflammatory bowel disease and iron deficiency anaemia in the Netherlands
    J Med Econ2026 DecPMID 42464571
  5. Physicochemical characterization of ferric carboxymaltose and iron sucrose nanoparticles in human plasma: stability and nanoparticle-protein complex formation
    J Colloid Interface Sci2026 DecPMID 42322714
  6. Response of reticulocyte and red blood cell indices to single-dose intravenous iron in pregnant women with moderate iron deficiency anemia: secondary analysis of the RAPIDIRON trial
    J Matern Fetal Neonatal Med2026 DecPMID 42045095RCT
  7. Effect of IV ferric carboxymaltose treatment on platelet counts and serum transferrin levels in CKD patients not on dialysis with iron deficiency: potential implications for thrombogenicity
    Ren Fail2026 DecPMID 41912474
  8. Nocturnal sleep-related scratching disorder as a possible variant of NREM arousal disorder: Clinical features and polysomnographic study of four newly reported cases
    Sleep Med X2026 DecPMID 41503364
  9. Management of restless legs syndrome when gabapentinoids fail: intravenous iron and opioids
    Curr Opin Pulm Med2026 Nov 1PMID 42713782Review
  10. Iron deficiency during pregnancy and lactation
    Curr Opin Clin Nutr Metab Care2026 Nov 1PMID 42681977Review

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How these numbers are counted

PubMed query, searched in titles and abstracts by publication date:

"intravenous iron"[tiab] OR "ferric carboxymaltose"[tiab] OR "ferric derisomaltose"[tiab]

Trials: ClinicalTrials.gov studies first submitted in each 12-month window that match the same terms. A query can miss synonyms or catch unrelated papers, so treat counts as approximate.